SAB5202071

Monoclonal Anti-beta 4 Spectrin-Horseradish Peroxidase antibody produced in mouse

clone S393-2, affinity isolated antibody, buffered aqueous solution

• Sinônimo(s): Anti-SPTBN4
• Código UNSPSC: 12352203
• NACRES: NA.45

Propriedades

• fonte biológica: mouse
• conjugado: peroxidase conjugate
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: S393-2; monoclonal
• descrição: clone S393-2, purified immunoglobulin, buffered aqueous solution; target molecular weight: 200 kDa
• Formulário: buffered aqueous solution
• reatividade de espécies: human (Tested), rat (Predicted), African green monkey (Tested), mouse (Predicted)
• embalagem: pkg of 100 μg
• condição de armazenamento: avoid repeated freeze/thaw cycles; protect from light
• concentração: 1.0 mg/mL
• técnica(s): immunofluorescence: 1:100; western blot: 1:1000
• Isotipo: IgG1
• nº de adesão UniProt: Q9H254
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... SPTBN4(57731)

Descrição

Imunogênio

Immunogen Description: Fusion protein amino acids 1621-1832 (C-terminal repeats 14 to 15) of human Beta4-spectrin

Immunogen Region: C-terminal

Immunogen Species: Human

Immunogen type: Fusion protein

Aplicação

Western blotting
Dilution 1:1000
Tissue/Cell Type Used: monkey COS-Beta-4-Spectrin-His

Immunofluorescence
Dilution 1:100
Tissue/Cell Type Used: SK-N-BE

forma física

50% glycerol, 0.1% sodium azide

PBS pH 7.4

Nota de preparo

Derived from animal serum

Armazenamento e estabilidade

Protect from light; avoid repeated freeze-thaw cycles. Store at -20 °C long-term, 2-8 °C short-term.

Outras notas

Additional Product Details:
Does not cross react with other Beta-spectrins
Lot Expiration/Retest Date: Expires 1 year from purchase

Target/Gene Description: Spectrin is the major constituent of the cytoskeletal network underlying the erthrocyte plasma membrane and determines cell shape, arrangement of transmembrane proteins and organization of organelles. It is expressed at very low levels in many tissues, with the strongest expression in the cerebellum, spinal cord, stomach, pituitary gland, liver, pancreas, salivary gland, kidney, bladder and heart . Spectrin beta 4 is a non-erythrocyte member, and is expressed in the brain and pancreatic islets and localisted to the nuclear matrix, cytoplasmic vesicles and PML nuclear bodies. Beta4 spectrins are also essential for membrane stability and the molecular organization of the nodes of Ranvier .
Purification method: Protein G purified
Product type: Primary antibody
Antibody structure: Whole Antibody
Protein ID: NP_066022.2

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable