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Key Documents

SAB4700590

Sigma-Aldrich

Monoclonal Anti-CD62L antibody produced in rat

clone MEL-14, purified immunoglobulin, buffered aqueous solution

Sinônimo(s):

Anti-L-selectin, Anti-Sell

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

fonte biológica

rat

conjugado

unconjugated

forma do anticorpo

purified immunoglobulin

tipo de produto de anticorpo

primary antibodies

clone

MEL-14, monoclonal

forma

buffered aqueous solution

reatividade de espécies

mouse

concentração

1 mg/mL

técnica(s)

flow cytometry: suitable

Isotipo

IgG2a

nº de adesão NCBI

NM_001164059.1

nº de adesão UniProt

P18337

Condições de expedição

wet ice

temperatura de armazenamento

2-8°C

modificação pós-traducional do alvo

unmodified

Informações sobre genes

mouse ... Sell(20343)

Descrição geral

The rat monoclonal antibody MEL-14 reacts with mouse CD62L (L-selectin), a 75 kDa single chain type I glycoprotein expressed on most peripheral blood B lymphocytes, T lymphocytes, monocytes and granulocytes; it is also present on a subset of NK cells and certain hematopoietic malignant cells.

Imunogênio

C3H/eb mouse B cell lymphoma 38C-13

Aplicação

The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 0.5 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

forma física

Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

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Código de classe de armazenamento

10 - Combustible liquids

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Certificados de análise (COA)

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Yulia Yu Silaeva et al.
Journal of immunotoxicology, 11(4), 393-399 (2013-12-07)
The concept of immunological surveillance implies that immunogenic variants of tumor cells arising in the organism can be recognized by the immune system. Tumor progression is provided by somatic evolution of tumor cells under the pressure of the immune system.
Alessandro Perrella et al.
Pathogens and disease, 72(2), 124-130 (2014-06-04)
We aimed to verify whether CD4(+)/CD25(+) T cells suppress CD4(+) T cells and secrete Granzyme B (GZB) during acute and chronic hepatitis C (CHC) infection. We enrolled 50 subjects: 20 patients with CHC (Group A), 15 healthy individuals (Group B)
Ira Eickmeier et al.
Journal of hepatology, 60(6), 1143-1150 (2014-02-25)
The enterohepatic circuit of T cells may be responsible for the development of autoimmune liver disease. We employed transgenic mice to characterize phenotype and migration patterns of CD8 T cells activated in liver and gut. We studied the migration of

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