SAB4504108

Anti-phospho-TIP60 (pSer⁸⁶) antibody produced in rabbit

affinity isolated antibody

• Sinônimo(s): KAT5, Lysine acetyltransferase 5
• Código UNSPSC: 12352203
• NACRES: NA.43

Propriedades

• fonte biológica: rabbit
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• forma: buffered aqueous solution
• peso molecular: antigen 58 kDa
• reatividade de espécies: rat, mouse, human
• concentração: ~1 mg/mL
• técnica(s): ELISA: 1:40000; western blot: 1:500-1:1000
• nº de adesão NCBI: Q92993
• nº de adesão UniProt: Q92993
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: phosphorylation (pSer86)
• Informações sobre genes: human ... KAT5(10524)

Descrição

Descrição geral

The TIP60 (HIV1 (human immunodeficiency virus 1)-TAT interactive protein) gene is mapped to human chromosome 11q13.1. It is ubiquitously expressed and evolutionarily conserved. The encoded protein, Tip60 belongs to the MYST (Moz, Ybf2/Sas3, Sas2 and TIP60) family.

Imunogênio

The antiserum was produced against synthesized peptide derived from human TIP60 around the phosphorylation site of Ser86.

Immunogen Range: 52-101

Aplicação

TIP60 (HIV1-TATinteractive protein) possess acetyltransferase activity and participates in chromatin remodeling and DNA damage repair. TIP60 is involved in protein stabilization and protein function modulation. The presence of chromodomain and MYST domain in its structure enables acetylation of both histone and non-histone proteins. TIP60 in association with androgenic receptors and transcription factors can control gene transcription and cell cycle process. TIP60 mediates p53 action to induce apoptosis. TIP60 inhibits Hepatitis B virus infection. TIP60 acts as a haploinsufficient tumor suppressor.

Características e benefícios

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forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable