SAB4501599

Anti-JAK2 antibody produced in rabbit

affinity isolated antibody

• Sinônimo(s): JAK-2, JAK2, Janus kinase 2, kinase Jak2
• Número MDL: MFCD00802820
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: antigen 130 kDa
• reatividade de espécies: mouse, rat, human
• concentração: ~1 mg/mL
• técnica(s): ELISA: 1:5000; immunofluorescence: 1:100-1:500; western blot: 1:500-1:1000
• nº de adesão NCBI: O60674
• nº de adesão UniProt: O60674
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... JAK2(3717)

Descrição

Descrição geral

Anti-JAK2 antibody detects endogenous levels of total JAK2 protein.

JAK2 (janus kinase 2) encodes a tyrosine kinase. It belongs to the the Jak family of proteins. It is located on human chromosome 9p24.

Imunogênio

The antiserum was produced against synthesized peptide derived from human JAK2.

Immunogen Range: 541-590

Ações bioquímicas/fisiológicas

JAK2 (janus kinase 2) plays an important role in the activities of cytokines receptors. Overexpression of JAK2 results in neuroblastoma. JAK2 mutations promote primary resistance to PD-1 (anti-programmed death protein 1) blockade therapy.

Características e benefícios

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forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): nwg
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable