SAB4501295

Anti-GLUR2 antibody produced in rabbit

affinity isolated antibody

• Sinônimo(s): GluR-2, GluR-B, GluR-K2, Glutamate receptor 2, Glutamate receptor ionotropic
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: antigen 98 kDa
• reatividade de espécies: human, mouse, rat
• concentração: ~1 mg/mL
• técnica(s): ELISA: 1:20000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• nº de adesão NCBI: P42262
• nº de adesão UniProt: P42262
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: unmodified
• Informações sobre genes: human ... GRIA2(2891)

Descrição

Descrição geral

Anti-GLUR2 Antibody detects endogenous levels of total GLUR2 protein.

GLUR2 (glutamate receptor 2) is coded by gria2 gene. It is mapped to human chromosome 4q32. It is abundantly expressed in the brain.

Imunogênio

The antiserum was produced against synthesized peptide derived from human GluR2.

Immunogen Range: 834-883

Aplicação

Anti-GLUR2, C-Terminal antibody has been used in electron microscopy.

Ações bioquímicas/fisiológicas

Presence of the glutamate receptor 2 (GluR2) subunit prevents calcium influx through AMPA-receptor complexes. Deletion of this subunit results in enhanced hippocampal long-term potentiation. As such, AMPA receptors play crucial roles in normal neuronal activity, including synaptic plasticity, synaptic scaling, homeostatic synaptic plasticity, learning and memory, as well as in synaptogenesis and the formation of neuronal circuitry.

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): nwg
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable