SAB4500662

Anti-Aggrecan (Cleaved-Asp³⁶⁹), N-Terminal antibody produced in rabbit

affinity isolated antibody

• Sinônimo(s): CSPCP, CSPG1, aggrecan core protein, cartilage-specific proteoglycan core protein, chondroitin sulfate proteoglycan core protein 1
• Código UNSPSC: 12352203
• NACRES: NA.41

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: antigen 44 kDa
• reatividade de espécies: human, rat
• concentração: ~1 mg/mL
• técnica(s): ELISA: 1:20000; immunohistochemistry: 1:50-1:100; western blot: 1:500-1:1000
• nº de adesão NCBI: P16112
• nº de adesão UniProt: P16112
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: proteolytically cleaved (Asp369)
• Informações sobre genes: human ... ACAN(176)

Descrição

Descrição geral

Anti-Aggrecan (Cleaved-Asp³⁶⁹) Antibody detects endogenous levels of fragment of activated Aggrecan (Cleaved-Asp³⁶⁹) protein.

Aggrecan is a large aggregating chondroitin sulfate proteoglycan of the human cartilage. It is encoded by AGC1 (aggrecan) gene. It is located on human chromosome 15q26.1.

Imunogênio

The antiserum was produced against synthesized peptide derived from human Aggrecan.

Immunogen Range: 320-369

Aplicação

Anti-Aggrecan (Cleaved-Asp369), N-Terminal antibody has been used in western blotting and immunostaining.

Ações bioquímicas/fisiológicas

Mutations in aggrecan results in autosomal dominant short stature with accelerated skeletal maturation. Mutation in the variable repeat region of the aggrecan gene (AGC1) leads to spondyloepiphyseal dysplasia.

Características e benefícios

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forma física

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): nwg
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable