SAB4300112

Anti-phospho-FOXO1 (pSer³¹⁹) antibody produced in rabbit

affinity isolated antibody

• Sinônimo(s): Anti-FKH1 antibody produced in rabbit, Anti-FKHR antibody produced in rabbit, Anti-FOXO1A antibody produced in rabbit, Anti-forkhead box O1 antibody produced in rabbit
• Número MDL: MFCD03791549
• Código UNSPSC: 12352203
• NACRES: NA.41
• conjugado: unconjugated
• application: IF; IHC (p); WB
• clone: polyclonal
• reatividade de espécies: rat, human, mouse
• citations: 1
• técnica(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000

Propriedades

• fonte biológica: rabbit
• Nível de qualidade: 100
• conjugado: unconjugated
• forma do anticorpo: affinity isolated antibody
• tipo de produto de anticorpo: primary antibodies
• clone: polyclonal
• Formulário: buffered aqueous solution
• peso molecular: 78-82 kDa
• reatividade de espécies: rat, human, mouse
• concentração: 1 mg/mL
• técnica(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000
• Isotipo: IgG
• sequência de imunogênio: (T-S-SP-N-A)
• nº de adesão NCBI: NP_002006.2
• nº de adesão UniProt: Q12778
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• modificação pós-traducional do alvo: phosphorylation (pSer319)
• Informações sobre genes: human ... FOXO1(2308)

Descrição

Imunogênio

Peptide sequence around phosphorylation site of serine 319 (T-S-S(p)-N-A), according to the protein FOXO1.

Características e benefícios

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Descrição-alvo

FKHR belongs to the forkhead family of transcription factors, which are characterized by a distinct forkhead domain. It may play a role in myogenic growth and differentiation. The mammalian DAF-16-like transcription factors, FKHR, FKHRL1, and AFX, function as key regulators of insulin signaling, cell cycle progression, and apoptosis downstream of phosphoinositide 3-kinase. Gene activation through binding to insulin response sequences has been essential for mediating these functions. D-type Cyclins (in Class III) is required for FKHR mediated inhibition of cell cycle progression and transformation. FKHR gene is mapped to chromosome 13q14.

forma física

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable