RAB1515
Human IL-12 R beta 2 ELISA
for serum, plasma and cell culture supernatants
Faça loginpara ver os preços organizacionais e de contrato
About This Item
Código UNSPSC:
41116158
NACRES:
NA.32
Produtos recomendados
![[Pd(OAc)2]3 reagent grade, 98%](/deepweb/assets/sigmaaldrich/product/structures/508/249/99a0ef2c-b77c-4d73-8ed9-0cca05b6b41f/640/99a0ef2c-b77c-4d73-8ed9-0cca05b6b41f.png)
reatividade de espécies
human
técnica(s)
ELISA: suitable
entrada
sample type plasma
sample type cell culture supernatant(s)
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
Condições de expedição
wet ice
temperatura de armazenamento
−20°C
Informações sobre genes
human ... IL12RB2(3595)
Descrição geral
The IL12RB2 (interleukin 12 receptor subunit β 2) gene is mapped to human chromosome 1p31.3 and codes for the β2 chain (130 kDa) of IL-12 receptor.
This ELISA antibody pair detects human IL-12 R beta 2. Other species not yet determined.
Aplicação
For research use only. Not for use in diagnostic procedures.
Please refer to the attached Protocolfor details.
Please refer to the attached Protocolfor details.
Ações bioquímicas/fisiológicas
Il12rb2 (interleukin 12 receptor subunit β 2) stimulates the release of interferon γ and Th1 (T helper cell 1) cell differentiation, as a part of autoimmune response. Il12rb2′s major function is associated with cell mediated immune system. In mice model, deletion of L12RB2 gene is associated with autoimmune and malignant disorders.
Outras notas
A sample Certificate of Analysis is available for this product. Please type the word sample in the text box provided for lot number.
Palavra indicadora
Warning
Frases de perigo
Declarações de precaução
Classificações de perigo
Met. Corr. 1
Código de classe de armazenamento
8A - Combustible corrosive hazardous materials
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Certificados de análise (COA)
Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.
Já possui este produto?
Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.
Identification of susceptibility SNPs in IL10 and IL23R-IL12RB2 for Behcet's disease in Han Chinese.
Yu H, et al.
The Journal of Allergy and Clinical Immunology, 139(2), 621-627 (2017)
IL12RB2 Polymorphisms correlate with risk of lung adenocarcinoma.
Prigione I, et al.
Immunobiol., 221(2), 291-299 (2016)
Association study of rs924080 and rs11209032 polymorphisms of IL23R-IL12RB2 in a Northern Chinese Han population with Behcet?s disease.
Qin X, et al.
Human immunology, 77(12), 1284-1290 (2016)
An ankylosing spondylitis-associated genetic variant in the IL23R-IL12RB2 intergenic region modulates enhancer activity and is associated with increased Th1-cell differentiation.
Roberts A R, et al.
Annals of the Rheumatic Diseases (2016)
Nahoko Kato-Kogoe et al.
Immunogenetics, 68(1), 55-65 (2015-11-11)
Interleukin 12 receptor β chain (IL12RB2) is a crucial regulatory factor involved in cell-mediated immune responses, and genetic variants of the gene encoding IL12RB2 are associated with susceptibility to various immune-related diseases. We previously demonstrated that haplotypes with single nucleotide
Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.
Entre em contato com a assistência técnica