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Merck
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Key Documents

R7882

Sigma-Aldrich

Retinyl acetate

BioReagent, solid or viscous liquid, synthetic, suitable for cell culture

Sinônimo(s):

Retinol acetate, Vitamin A acetate

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About This Item

Fórmula empírica (Notação de Hill):
C22H32O2
Número CAS:
Peso molecular:
328.49
Beilstein:
1915439
Número CE:
Número MDL:
Código UNSPSC:
12352205
eCl@ss:
34058009
ID de substância PubChem:
NACRES:
NA.75

fonte biológica

synthetic

Nível de qualidade

linha de produto

BioReagent

Ensaio

≥90% (HPLC)

forma

solid or viscous liquid

potência

~2,800,000 I.U. per g

peso molecular

Mw 328.49 g/mol

técnica(s)

cell culture | mammalian: suitable

cor

light yellow to dark yellow

pf

57-58 °C

solubilidade

absolute ethanol: 25 mg/mL (lit.)

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(C)=O)C(C)(C)CCC1

InChI

1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+

chave InChI

QGNJRVVDBSJHIZ-QHLGVNSISA-N

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Descrição geral

Retinyl-acetate is a natural and ester derivative of vitamin A. It is found in classical media formulations such as M-199; NCTC-109 and William′s Medium E. Vitamin A is a component of serum useful in most serum containing cell culture systems, which receive some level of vitamin A.

Aplicação

Retinyl acetate has been used as a standard to measure the concentration of vitamin C in high performance liquid chromatography analysis (HPLC) and as a supplement in the preparation of the complete medium.

Ações bioquímicas/fisiológicas

The oxidized form of retinol is retinoic acid, which has hormone-like growth factor and differentiation activity for epithelial and related cell types, especially neural cells. Retinoic acid induces embryonic stem cells to differentiate towards neural cells. Retinyl-acetate is known to be effective in treating breast cancer.

Outras notas

All trans

Nota de preparo

The melting point of this material is approx. 58 °C. In order to package, it was melted and may exist as a crystalline solid or as a supercooled viscous liquid.

Pictogramas

Health hazard

Palavra indicadora

Danger

Frases de perigo

Classificações de perigo

Aquatic Chronic 4 - Repr. 1B

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 2

Equipamento de proteção individual

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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Artigos

All-trans retinoic acid (RA, ATRA) is a pleiotropic activation factor that regulates genes associated with normal vertebrate cellular processes such as cell differentiation, cell proliferation, apoptosis, and embryonic development.

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