R4632

Retinyl acetate

synthetic, crystalline solid or supercooled liquid

• Sinônimo(s): Retinol acetate, Vitamin A acetate
• Fórmula empírica (Notação de Hill): C₂₂H₃₂O₂
• Número CAS: 127-47-9
• Peso molecular: 328.49
• Beilstein: 1915439
• Número CE: 204-844-2
• Número MDL: MFCD00019413
• Código UNSPSC: 12352205
• eCl@ss: 34058009
• ID de substância PubChem: 57654592
• NACRES: NA.79

Propriedades

• fonte biológica: synthetic
• Ensaio: ≥90% (HPLC)
• Formulário: crystalline solid or supercooled liquid
• potência: 2,600,000-2,940,000 I.U. per g
• cor: light yellow to dark yellow
• pf: 57-58 °C; ~58 °C (lit.)
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: CC1=C(/C=C/C(C)=C/C=C/C(C)=C/COC(C)=O)C(C)(C)CCC1
• InChI: 1S/C22H32O2/c1-17(9-7-10-18(2)14-16-24-20(4)23)12-13-21-19(3)11-8-15-22(21,5)6/h7,9-10,12-14H,8,11,15-16H2,1-6H3/b10-7+,13-12+,17-9+,18-14+
• chave InChI: QGNJRVVDBSJHIZ-QHLGVNSISA-N

Descrição

Descrição geral

Vitamin A usually occurs in food as retinyl esters, which are the pre-formed sources of vitamin A. Retinyl acetate exists as yellow crystals and is insoluble in water. It is soluble in ethanol and oils.

Aplicação

Retinyl acetate has been used:

• to study its effects on cochlear development in mice
• as a component of an internal standard to quantify antioxidants in yolk
• as an internal standard to determine serum retinol concentration

Ações bioquímicas/fisiológicas

Retinal, retinol and retinoic acid are the aldehyde, alcohol and acid forms of vitamin A. The retinoids exist as many geometric isomers due to the unsaturated bonds in the aliphatic chain.
Retinoids also exist as retinyl esters such as retinyl propionate, retinyl acetate and retinyl palmitate. Retinyl esters provide pools of vitamin A that are converted into retinol and other retinoids as needed. Retinyl acetate is used in a wide range of biological applications.

forma física

Packaged as a melt and may exist as a crystalline solid or a supercooled viscous liquid

Nota de análise

Activity based on HPLC comparison to USP standard.

Informações de segurança

• Pictogramas: GHS08
• Palavra indicadora: Danger
• Frases de perigo: H360D,H413
• Declarações de precaução: P202 - P273 - P280 - P308 + P313 - P405 - P501
• Classificações de perigo: Aquatic Chronic 4 - Repr. 1B
• Código de classe de armazenamento: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type ABEK (EN14387) respirator filter