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Key Documents

PLA0304

Sigma-Aldrich

Goat anti-HIF1-alpha Antibody, Affinity Purified

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Sinônimo(s):

ARNT interacting protein, ARNT-interacting protein, HIF-1-alpha, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PAS domain-containing protein 8, PASD8, alpha subunit (basic helix-loop-helix transcription factor), bHLHe78, basic-helix-loop-helix-PAS protein MOP1, class E basic helix-loop-helix protein 78, hypoxia inducible factor 1, hypoxia-inducible factor 1, hypoxia-inducible factor 1 alpha isoform I.3, hypoxia-inducible factor1alpha, member of PAS protein 1, member of PAS superfamily 1

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

fonte biológica

goat

Nível de qualidade

100

forma do anticorpo

affinity purified immunoglobulin

tipo de produto de anticorpo

primary antibodies

grau

Powered by Bethyl Laboratories, Inc.

reatividade de espécies

human

concentração

1 mg/mL

técnica(s)

immunoprecipitation (IP): 2- 10 μg/mg

nº de adesão

NP_001521.1

Condições de expedição

wet ice

temperatura de armazenamento

2-8°C

Informações sobre genes

goat ... HIF1-alpha(3091)

Imunogênio

The epitope recognized by PLA0304 maps to a region between residue 776 and 826 of human Hypoxia-Inducible Factor 1, Alpha Subunit using the numbering given in entry NP_001521.1 (GeneID 3091).

forma física

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Outras notas

Hypoxia-inducible factor-1 (HIF1) is a basic helix-loop-helix (bHLH)-PER-ARNT-sim (PAS) transcription factor that plays a role in the cellular response to hypoxia. HIF1 is a heterodimer of an HIF1-alpha and HIF1-beta subunit. During normoxia, HIF-1alpha is regulated by ubiquitination and interaction with the von-Hippel-Lindau tumor suppressor protein (pVHL).

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

12 - Non Combustible Liquids

Classe de risco de água (WGK)

nwg

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Junhua Mao et al.
American journal of physiology. Renal physiology, 307(9), F1023-F1032 (2014-07-06)
Podocytes play a key role in the formation of cellular crescents in experimental and human diseases. However, the underlying mechanisms for podocytes in promoting crescent formation need further investigation. Here, we demonstrated that mammalian target of rapamycin complex 1 (mTORC1)

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