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Documentos Principais

PLA0236

Sigma-Aldrich

Anti-KRAS Antibody

from rabbit

Sinônimo(s):

ERK, ERK-2, ERK2, ERT1, MAP kinase 1, MAP kinase 2, MAP kinase isoform p42, MAPK 1, MAPK 2, MAPK2, P42MAPK, PRKM1, PRKM2, extracellular signal-regulated kinase 2, mitogen-activated protein kinase 2, p38, p40, p41, p41mapk, p42-MAPK, protein tyrosine kinase ERK2

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About This Item

Código UNSPSC:
12352203
NACRES:
NA.41

Nome do produto

Rabbit anti-ERK2 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.

fonte biológica

rabbit

Nível de qualidade

100

forma do anticorpo

affinity purified immunoglobulin

tipo de produto de anticorpo

primary antibodies

grau

Powered by Bethyl Laboratories, Inc.

reatividade de espécies

human, mouse

técnica(s)

immunohistochemistry: 1:500- 1:2,000
western blot: 1:2,000- 1:10,000

nº de adesão

NP_002736.3

Condições de expedição

wet ice

temperatura de armazenamento

2-8°C

Informações sobre genes

rabbit ... ERK2(5594)

Imunogênio

The epitope recognized by PLA0236 maps to a region between residue 310 and 360 of human extracellular signal-regulated kinase-2 (mitogen-activated protein kinase 1) using the numbering given in entry NP_002736.3 (GeneID 5594).

forma física

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Outras notas

Extracellular signal-regulated kinase 2 (ERK2/p42) is also known as mitogen-activated protein kinase 1 (MAPK1). ERK2 is part of a signal transduction pathway that begins with the small GTPase Ras and continues through a cascade of protein kinases that include Raf and MEK. Activation of this signaling pathway influences many cellular processes such as proliferation, differentiation and survival. ERK2 is very similar in sequence to ERK1/p44 and the activities of both ERK1 and ERK2 are usually considered together as total ERK activity. More recent evidence has shown that ERK1 and ERK2 are not functionally redundant and may have very different and specific roles.

Exoneração de responsabilidade

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Código de classe de armazenamento

12 - Non Combustible Liquids

Classe de risco de água (WGK)

nwg

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Certificados de análise (COA)

Lot/Batch Number

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