P9797

Pyridostigmine bromide

• Sinônimo(s): 3-(Dimethylaminocarbonyloxy)-1-methylpyridinium bromide
• Fórmula empírica (Notação de Hill): C₉H₁₃BrN₂O₂
• Número CAS: 101-26-8
• Peso molecular: 261.12
• Número CE: 202-929-9
• Número MDL: MFCD00079283
• Código UNSPSC: 12352200
• ID de substância PubChem: 24277865
• NACRES: NA.77

Propriedades

• Ensaio: ≥98% (HPLC)
• Nível de qualidade: 100
• Formulário: solid
• solubilidade: water: 100 mg/mL, clear to very slightly hazy, colorless
• originador: Valeant
• cadeia de caracteres SMILES: [Br-].CN(C)C(=O)Oc1ccc[n+](C)c1
• InChI: 1S/C9H13N2O2.BrH/c1-10(2)9(12)13-8-5-4-6-11(3)7-8;/h4-7H,1-3H3;1H/q+1;/p-1
• chave InChI: VNYBTNPBYXSMOO-UHFFFAOYSA-M
• Informações sobre genes: human ... ACHE(43)

Descrição

Aplicação

Pyridostigmine bromide has been used as a cholinesterase inhibitor in mice, in florimetric assay for acetylcholine secretion and for measuring acetylcholine release from mice atrial tissue.

Ações bioquímicas/fisiológicas

Pyridostigmine bromide inhibits acetylcholine esterase and is membrane impermeable. It is used as a preventive medicine in chemical warfare. Pyridostigmine bromide is a carbamate compound comprising quaternary amine structure. It displays low absorption at the gastrointestinal tract. Sustained release of pyridostigmine is recommended for improving its bioavailability in treating myasthenia gravis.

Acetylcholinesterase inhibitor.

Características e benefícios

This compound was developed by Valeant. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Informações de segurança

• Pictogramas: GHS06
• Palavra indicadora: Danger
• Frases de perigo: H300 + H310 + H330,H317
• Declarações de precaução: P262 - P280 - P301 + P310 + P330 - P302 + P352 + P310 - P304 + P340 + P310
• Classificações de perigo: Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Skin Sens. 1
• Código de classe de armazenamento: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges