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P8877

Sigma-Aldrich

D-(−)-3-Phosphoglyceric acid disodium salt

greener alternative

≥93% dry basis (enzymatic), powder

Sinônimo(s):

(−)-Disodium D-3-phosphoglycerate, D-Glycerate 3-phosphate disodium salt

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About This Item

Fórmula empírica (Notação de Hill):
C3H5Na2O7P
Número CAS:
Peso molecular:
230.02
Beilstein:
3767836
Número MDL:
Código UNSPSC:
12352201
ID de substância PubChem:
NACRES:
NA.25

fonte biológica

synthetic (inorganic)

Nível de qualidade

Ensaio

≥93% dry basis (enzymatic)

Formulário

powder

características do produto alternativo mais ecológico

Atom Economy
Design for Energy Efficiency
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

Impurezas

<14% water (NMR)

cor

white

solubilidade

H2O: 50 mg/mL, clear, colorless to faintly yellow

traços de cátion

Na: 18-22% (dry basis)

categoria alternativa mais ecológica

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

[Na+].[Na+].O[C@H](COP(O)([O-])=O)C([O-])=O

InChI

1S/C3H7O7P.2Na/c4-2(3(5)6)1-10-11(7,8)9;;/h2,4H,1H2,(H,5,6)(H2,7,8,9);;/q;2*+1/p-2/t2-;;/m1../s1

chave InChI

RGCJWQYUZHTJBE-YBBRRFGFSA-L

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Aplicação

D-(-)-3-Phosphoglyceric acid disodium salt has been used in a study to assess the phosphorylation of glyceric acid in aqueous solution. It has also been used in a study to characterize a glutathione- and NAD-dependent arsenate reduction linked to glycolysis.

Ações bioquímicas/fisiológicas

3-Phosphoglyceric acid is an intermediate in glycolysis. It also a precursor in the formation of serine.

Outras notas

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Pictogramas

Health hazardExclamation mark

Palavra indicadora

Warning

Frases de perigo

Classificações de perigo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 2 - STOT SE 3

Órgãos-alvo

Eyes,Central nervous system, Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3


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V Kolb et al.
Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 26(1), 7-13 (1996-02-01)
The phosphorylation of glyceric acid is an interesting prebiotic reaction because it converts a simple, potentially prebiotic organic molecule into phosphate derivatives that are central to carbohydrate metabolism. We find that 0.05 M glyceric acid in the presence of 0.5
Balázs Németi et al.
Toxicological sciences : an official journal of the Society of Toxicology, 85(2), 847-858 (2005-03-25)
Reduction of arsenate (AsV) to the more toxic arsenite (AsIII) is of high toxicological importance, yet in vivo relevant enzymes involved have not been identified. Purine nucleoside phosphorylase (PNP) is an efficient AsV reductase in vitro, but its role in
Jeremy M Foster et al.
PloS one, 5(10), e13576-e13576 (2010-12-29)
The glycolytic phosphoglycerate mutases exist as non-homologous isofunctional enzymes (NISE) having independent evolutionary origins and no similarity in primary sequence, 3D structure, or catalytic mechanism. Cofactor-dependent PGM (dPGM) requires 2,3-bisphosphoglycerate for activity; cofactor-independent PGM (iPGM) does not. The PGM profile
Liangchun Yang et al.
Nature communications, 5, 4436-4436 (2014-07-16)
Increasing evidence suggests the important role of metabolic reprogramming in the regulation of the innate inflammatory response, but the underlying mechanism remains unclear. Here we provide evidence to support a novel role for the pyruvate kinase M2 (PKM2)-mediated Warburg effect

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