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P3584

Sigma-Aldrich

L-α-Phosphatidyl-D-myo-inositol 4,5-diphosphate, dioctanoyl

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About This Item

Fórmula empírica (Notação de Hill):
C25H49O19P3
Número CAS:
204858-53-7
Peso molecular:
746.57
Número MDL:
MFCD02259161
Código UNSPSC:
12352207
ID de substância PubChem:
24898428
NACRES:
NA.77

forma

powder

Nível de qualidade

100

solubilidade

H2O: soluble

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

CCCCCCCC(=O)OC[C@H](COP(O)(=O)O[C@@H]1[C@H](O)[C@H](O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H]1O)OC(=O)CCCCCCC

InChI

1S/C25H49O19P3/c1-3-5-7-9-11-13-18(26)39-15-17(41-19(27)14-12-10-8-6-4-2)16-40-47(37,38)44-23-20(28)21(29)24(42-45(31,32)33)25(22(23)30)43-46(34,35)36/h17,20-25,28-30H,3-16H2,1-2H3,(H,37,38)(H2,31,32,33)(H2,34,35,36)/t17-,20-,21+,22+,23-,24-,25-/m1/s1

chave InChI

XLNCEHRXXWQMPK-MJUMVPIBSA-N

Características e benefícios

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Substratos

Signaling lipid which apparently acts by binding to pleckstrin homology domains; direct activator of inward rectifier potassium channels; phospholipase C and PI3-kinase substrate; activates phospholipase D.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Jillian C Carmichael et al.
Virology, 527, 64-76 (2018-11-23)
Glycoprotein D (gD) of herpes simplex virus type 1 (HSV-1) plays a key role in multiple events during infection including virus entry, cell-to-cell spread, and virus-induced syncytia formation. Here, we provide evidence that an arginine/lysine cluster located at the transmembrane-cytoplasm
J E Harlan et al.
Biochemistry, 34(31), 9859-9864 (1995-08-08)
The pleckstrin homology (PH) domain is a protein module of approximately 100 amino acids that is found in several proteins involved in signal transduction [for a recent review, see Gibson et al. (1994) Trends Biochem. Sci. 19, 349-353]. Although the
C L Huang et al.
Nature, 391(6669), 803-806 (1998-03-05)
Inward rectifier K+ channels, which modulate electrical activity in many cell types, are regulated by protein kinases, guanine-nucleotide-binding proteins (G proteins) and probably actin cytoskeleton. Generation of phosphatidylinositol 4,5-bisphosphate (PIP2) by ATP-dependent lipid kinases is known to activate inward rectifier
J A Pitcher et al.
The Journal of biological chemistry, 270(20), 11707-11710 (1995-05-19)
The pleckstrin homology (PH) domain is an approximately 100-amino-acid region of sequence homology present in numerous proteins of diverse functions, which forms a discrete structural module. Several ligands capable of binding to PH domain-containing proteins have been identified including phosphatidylinositol

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