P3556

L-αfosfatidilcolina

egg yolk, Type XVI-E, ≥99% (TLC), lyophilized powder

• Sinônimo(s): 1,2-Diacil-sn-glicero-3-fosfocolina, 3-sn-fosfatidilcolina, L-αlecitina, Azolectina, PC
• Número CAS: 8002-43-5
• Beilstein: 5209585
• Número CE: 232-307-2
• Código UNSPSC: 51321705
• NACRES: NA.25

Propriedades

• fonte biológica: egg yolk
• Nível de qualidade: 200
• tipo: Type XVI-E
• Ensaio: ≥99% (TLC)
• Formulário: lyophilized powder
• grupo funcional: phospholipid
• tipo de lipídio: phosphoglycerides
• Condições de expedição: ambient
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: [P](=O)([O-])(OC[C@H](OC(=O)CCCCCCC\C=C/C\C=C/CCCCC)COC(=O)CCCCCCCCCCCCCCC)OCC[N+](C)(C)C
• InChI: 1S/C42H80NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h14,16,20-21,40H,6-13,15,17-19,22-39H2,1-5H3/b16-14-,21-20-/t40-/m1/s1
• chave InChI: JLPULHDHAOZNQI-ZTIMHPMXSA-N

Descrição

Descrição geral

Phosphatidylcholine belongs to the class of glycerophoshpolipids and contains choline as the head-group. Choline is attached to the glycerol of fatty acids ester-bound to backbone. It is the major phospholipid found in eukaryotic organism.

Aplicação

L-α-Phosphatidylcholine has been used:

• to form a thin lipid film used in Kupffer cell depletion by liposome-encapsulated clodronate
• as a component of assay buffer used in γ-secretase in vitro assay
• in the preparation of substrate mix for its use in HPLC (high performance liquid chromatography) assay of 5-lipoxygenase enzyme activity

Ações bioquímicas/fisiológicas

Fosfolipídio estrutural importante no cérebro, contendo cerca de 15% de lipídios no total, localizado principalmente na massa cinzenta.

It also acts as a source of lipid messengers/ bioactive lipids including: lysophosphatidylcholine, diacylglycerol, phosphatidic acid, lysophosphatidylcholine, arachidonic acid and platelet activating factor. Phosphatidylcholine is produced in the liver by the CDP-choline (cytidine diphosphocholine) pathway.

Embalagem

Packaged under Argon

Nota de preparo

Prepared by a modification of the procedure of Singleton, W.S., et al., J. Am. Oil Chem. Soc., 42, 53 (1965).

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)