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P2795

Sigma-Aldrich

Phytosphingosine hydrochloride

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Sinônimo(s):

4-Hydroxysphinganine, D-Ribo-1,3,4-trihydroxy-2-aminooctadecane, D-Ribo-2-aminooctadecane-1,3,4-triol, PHS

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About This Item

Fórmula empírica (Notação de Hill):
C18H39NO3 · HCl
Número CAS:
554-62-1
Peso molecular:
353.97
Número MDL:
MFCD06804643
Código UNSPSC:
12352211
ID de substância PubChem:
24898363
NACRES:
NA.25

Formulário

powder

Nível de qualidade

200

pontuação do produto alternativo mais ecológico

old score: 19
new score: 9
Find out more about DOZN™ Scoring

características do produto alternativo mais ecológico

Less Hazardous Chemical Syntheses
Safer Solvents and Auxiliaries
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

categoria alternativa mais ecológica

, Re-engineered

tipo de lipídio

sphingolipids

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

Cl.CCCCCCCCCCCCCC[C@@H](O)[C@@H](O)[C@@H](N)CO

InChI

1S/C18H39NO3.ClH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(21)18(22)16(19)15-20;/h16-18,20-22H,2-15,19H2,1H3;1H/t16-,17+,18-;/m0./s1

chave InChI

GDKAAHDFPOWGQE-RXQQAGQTSA-N

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Ações bioquímicas/fisiológicas

Phytosphingosine is a long chain sphingoid base that occurs broadly in yeast, plants and animals including mammals. In yeast it is involved in mediating the heat stress response, perhaps through activation of the AGC-type protein kinases, Pkh1, Pkh2, Ypk1, Ypk2, and Sch9. It is proapoptotic in human cancer cell lines. PHS induces ΔΨm and release of cytochrome c from mitochondria either directly or through activation of p38 MAPK pathway. This leads to activation of caspase 9 followed by activation of caspase 3 and programmed cell death.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

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Certificados de análise (COA)

Lot/Batch Number
126M4088V
029M4159V
14180603
097M4113V
14170805

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