860490P

Sphingosine (d18:1)

Avanti Research^™ - A Croda Brand

• Sinônimo(s): D-erythro-sphingosine
• Fórmula empírica (Notação de Hill): C₁₈H₃₇NO₂
• Número CAS: 123-78-4
• Peso molecular: 299.49
• Código UNSPSC: 12352211
• NACRES: NA.25

Propriedades

• Formulário: powder
• embalagem: pkg of 1 × 10 mg (860490P-10mg); pkg of 1 × 25 mg (860490P-25mg); pkg of 1 × 500 mg (860490P-500mg)
• fabricante/nome comercial: Avanti Research^™ - A Croda Brand
• tipo de lipídio: sphingolipids
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: OC[C@@](N)([H])[C@]([H])(O)/C=C/CCCCCCCCCCCCC
• InChI: 1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h14-15,17-18,20-21H,2-13,16,19H2,1H3/b15-14+/t17-,18+/m0/s1
• chave InChI: WWUZIQQURGPMPG-KRWOKUGFSA-N

Descrição

Descrição geral

Sphingosine (d18:1) is a spingoid base present in plant and animals. It has 2-amino-1,3-diol functionality and its extraction from animal tissue is laborious. Sphingosine (d18:1) synthesis is performed by chirospecific method using D-galactose.

Aplicação

Sphingosine (d18:1) has been used:

• for sphingosine inhalations studies in mice to evaluate its therapeutic potential in respiratory epithelial cells
• to investigate its effect on Pseudomonas aeruginosa strains
• as a standard in liquid chromatography tandem mass spectrophotometry for the quantification of epidermal ceramides

Ações bioquímicas/fisiológicas

Sphingosine (d18:1) is essential for physiological processes including cell differentiation, growth and survival. It activates the transient receptor potential cation channel subfamily member 3 (TRPM3).

Embalagem

20 mL Clear Glass Screw Cap Vial (860490P-500mg)

5 mL Amber Glass Screw Cap Vial (860490P-10mg)

5 mL Amber Glass Screw Cap Vial (860490P-25mg)

Informações legais

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Informações de segurança

• Frases de perigo: H413
• Declarações de precaução: P273 - P501
• Classificações de perigo: Aquatic Chronic 4
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable