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P1152

Sigma-Aldrich

Poly(Ala, Glu, Lys, Tyr) 6:2:5:1 hydrobromide

greener alternative

Ala:Glu:Lys:Tyr (6:2:5:1), mol wt 20,000-30,000

Sinônimo(s):

(L-Ala, L-Glu, L-Lys, L-Tyr)n ·HBr, COP-1

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About This Item

Número CAS:
28704-27-0
Número MDL:
MFCD00166401
Código UNSPSC:
12352202
NACRES:
NA.26

Formulário

powder

Nível de qualidade

200

proporção de alimentação

Ala:Glu:Lys:Tyr (6:2:5:1)

peso molecular

20,000-30,000

pontuação do produto alternativo mais ecológico

old score: 56
new score: 39
Find out more about DOZN™ Scoring

características do produto alternativo mais ecológico

Designing Safer Chemicals
Safer Solvents and Auxiliaries
Reduce Derivatives
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

cor

white to off-white

categoria alternativa mais ecológica

, Re-engineered

temperatura de armazenamento

−20°C

InChI

1S/C9H11NO3.C6H14N2O2.C5H9NO4.C3H7NO2/c10-8(9(12)13)5-6-1-3-7(11)4-2-6;7-4-2-1-3-5(8)6(9)10;6-3(5(9)10)1-2-4(7)8;1-2(4)3(5)6/h1-4,8,11H,5,10H2,(H,12,13);5H,1-4,7-8H2,(H,9,10);3H,1-2,6H2,(H,7,8)(H,9,10);2H,4H2,1H3,(H,5,6)/t8-;5-;3-;2-/m0000/s1

chave InChI

YLOCGHYTXIINAI-XKUOMLDTSA-N

Descrição geral

We are committed to bringing you Greener Alternative Products, which adhere to one of the four categories of Greener Alternatives . This product belongs to category of Re-engineered products, showing key improvements in Green Chemistry Principles “Designing Safer Chemicals”, "Safer Solvents and Auxiliaries" and “Reduce Derivatives”. Click here to view its DOZN scorecard.

Ações bioquímicas/fisiológicas

Poly(Ala, Glu, Lys, Tyr) 6:2:5:1 hydrobromide is a polyamino acid reported to have a suppressive effect on allergic encephalomyelitis.
Reported to have suppressive effect on experimental allergic encephalomyelitis induced in laboratory animals.

Nota de análise

Reported molecular weight based on viscosity.

Outras notas

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

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Certificados de análise (COA)

Lot/Batch Number
SLBH2744V
090M5003V
090M5003
074K5106
083K5114

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M Sela
Applied biochemistry and biotechnology, 83(1-3), 63-70 (2000-05-29)
The conformation of a peptide defines its antigenic specificity. In most cases, a free peptide is in a random form, whereas the same peptide within a protein has a defined conformation. Immunological cross-reactions between the two are rare. Nevertheless, there
E Zisman et al.
European journal of immunology, 24(10), 2497-2505 (1994-10-01)
Studies with the well-characterized, synthetic, random-multichain polypeptide poly(LTyr,LGlu)-poly(DLAla)-poly(LLys) (T,G)-A-L) led to the discovery of determinant-specific genetic control of the immune response, as well as to other immunological phenomena. Moreover, the tetrapeptide TyrTyrGluGlu built on the same backbone ("(T-T-G-G)-A--L") was found
Expanded clinical trials of treatments for multiple sclerosis: copolymer 1 (COP-1) treatment investigational new drug (IND) program.
Y Stark
Annals of neurology, 36(1), 114-115 (1994-07-01)
Carmen C M Chan
Recent patents on CNS drug discovery, 3(3), 189-199 (2008-11-11)
Spinal cord injury leads to a devastating cascade of secondary complications that eventually results in the formation of scar tissue many times the size of the original insult. Inflammation plays a very important role towards the development of such scar
Byoung-Joo Choi et al.
Japanese heart journal, 45(4), 697-702 (2004-09-09)
A 16 year-old Korean girl with cardiomegaly was found to have a "right atrial cystic mass" on transthoracic echocardiography. An unusual cystic structure made the diagnosis difficult. However, transesophageal echocardiography and multidetector computed tomography revealed a coronary artery fistula with
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