O2136

Oleamide

≥99% (TLC), powder, sleep-inducing brain lipid

• Sinônimo(s): cis-9,10-Octadecenoamide, cis-9-Octadecenamide, Oleic acid amide
• Fórmula empírica (Notação de Hill): C₁₈H₃₅NO
• Número CAS: 301-02-0
• Peso molecular: 281.48
• Número CE: 206-103-9
• Número MDL: MFCD00053638
• Código UNSPSC: 12352200
• ID de substância PubChem: 24897957
• NACRES: NA.77

Propriedades

• product name: Oleamide, ≥99%
• Nível de qualidade: 200
• Ensaio: ≥99%
• controle de medicamentos: regulated under CDSA - not available from Sigma-Aldrich Canada
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: CCCCCCCC\C=C/CCCCCCCC(N)=O
• InChI: 1S/C18H35NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H2,19,20)/b10-9-
• chave InChI: FATBGEAMYMYZAF-KTKRTIGZSA-N

Descrição

Descrição geral

Oleamide is a lipid or a brain fatty acid, that is found in the CSF (cerebrospinal fluid). It is originally obtained from the cerebrospinal fluid of cats, that are sleep-deprived.

Aplicação

Oleamide has been used as a supplement in glucose and galactose media to prevent the rescue of galactose-induced Leigh syndrome (LS).

Ações bioquímicas/fisiológicas

Oleamide has the ability to stimulate sleep. It possess several properties, like cannabinoid-like activity. Oleamide can also disable the communication, facilitated by gap junction between rat glial cells.

Sleep-inducing brain lipid, which allosterically modulates GABA_A receptors and potentiates 5-HT₇ serotonin receptor responses. Selective endogenous agonist of rat and human CB1 cannabinoid receptor.

Informações de segurança

• Frases de perigo: H413
• Declarações de precaução: P273 - P501
• Classificações de perigo: Aquatic Chronic 4
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): 404.6 °F - closed cup
• Ponto de fulgor (°C): 207 °C - closed cup
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Faceshields, Gloves