N5538
Monoclonal Anti-3-Nitrotyrosine antibody produced in mouse
clone 18G4, purified immunoglobulin, buffered aqueous glycerol solution
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About This Item
Código UNSPSC:
12352203
NACRES:
NA.41
conjugado:
unconjugated
application:
WB
clone:
18G4, monoclonal
reatividade de espécies:
wide range
citations:
17
técnica(s):
western blot: 1:1,000 using mouse and rat brain
Produtos recomendados
fonte biológica
mouse
conjugado
unconjugated
forma do anticorpo
purified immunoglobulin
tipo de produto de anticorpo
primary antibodies
clone
18G4, monoclonal
Formulário
buffered aqueous glycerol solution
peso molecular
antigen ~55 kDa
reatividade de espécies
wide range
técnica(s)
western blot: 1:1,000 using mouse and rat brain
Condições de expedição
wet ice
temperatura de armazenamento
−20°C
modificação pós-traducional do alvo
nitration (Tyr)
Informações sobre genes
human ... NOS1(4842)
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Descrição geral
3-nitrotyrosine (3-NT) is synthesized by the incorporation of nitro triatomic group (-NO2) at the third position of the phenolic ring in the tyrosine residue, in response to the production of peroxynitrite in the oxidative and nitrosative stress.
Imunogênio
3-Nitrotyrosine-KLH.
Aplicação
Monoclonal Anti-3-Nitrotyrosine antibody produced in mouse has been used in western blot analysis and immunohistochemistry.
Ações bioquímicas/fisiológicas
3-Nitrotyrosine (3-NT) in tissue extracts is a marker for the determination of protein damage induced by peroxynitrite. 3-NT is used as a biomarker to determine the protein nitration, associated with various disorders. It is implicated in diseases characterized by endothelial dysfunction as in stroke, myocardial infarction, atherosclerosis and diabetes.
Descrição-alvo
Monoclonal Anti-3-Nitrotyrosine recognizes 3-nitrotyrosine in most species. Protein tyrosine nitration results in a post-translational modification that is increasingly receiving attention as an important component of nitric oxide signaling.
forma física
Solution in 20 mM sodium phosphate, 150 mM sodium chloride, 50% glycerol, and 3 mM sodium azide.
Exoneração de responsabilidade
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Código de classe de armazenamento
10 - Combustible liquids
Classe de risco de água (WGK)
WGK 2
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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Industrial Crops and Products, 52, 815-826 (2014)
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Journal of neuroscience research, 93(11), 1728-1739 (2015-08-08)
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