N1638

Nystatin Suspension

suspension, non-animal origin, suitable for cell culture, BioReagent

• Sinônimo(s): Fungicidin, Mycostatin
• Número CAS: 1400-61-9
• Código UNSPSC: 12352207
• ID de substância PubChem: 24897511
• NACRES: NA.76

Propriedades

• product name: Nystatin Suspension, suspension, 10,000 unit/mL in DPBS, BioReagent, suitable for cell culture
• linha de produto: BioReagent
• Nível de qualidade: 200
• forma: suspension
• concentração: 10,000 unit/mL in DPBS
• técnica(s): cell culture | mammalian: suitable
• Impurezas: endotoxin, tested
• cor: yellow
• espectro de atividade do antibiótico: fungi; yeast
• Modo de ação: cell membrane | interferes
• Condições de expedição: dry ice
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: C[C@@H]1OC(=O)C[C@H](O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@]2(O)C[C@H](O)[C@H]([C@H](C[C@@H](O[C@@H]3O[C@H](C)[C@@H](O)[C@H](N)[C@@H]3O)\C=C\C=C\C=C\C=C\CC\C=C\C=C\[C@H](C)[C@@H](O)[C@@H]1C)O2)C(O)=O
• InChI: 1S/C47H75NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-36(53)35(52)20-19-31(49)21-32(50)22-33(51)23-39(55)62-29(3)28(2)42(27)56/h5-6,8,10-18,27-38,40-44,46,49-54,56-58,61H,7,9,19-26,48H2,1-4H3,(H,59,60)/b6-5+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28+,29-,30+,31+,32+,33+,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1
• chave InChI: VQOXZBDYSJBXMA-QEKUPDCNSA-N

Descrição

Descrição geral

Chemical structure: polyene

Aplicação

Nystatin suspension has been used:

• to inhibit caveolin-mediated endocytosis
• as a component of Eagle′s minimum essential medium (EMEM)
• to enumerate lactic acid bacteria (LAB)
• in preventing cell culture contamination and inducing interleukin (IL)-1, IL-8, and tumor necrosis factor a secretion in toll-like receptor 2 (TLR2)-expressing THP1 cells.

This product is recommended for use in cell culture applications at 24 mL/L.

Ações bioquímicas/fisiológicas

Nystatin is a polyene, broad-spectrum antibiotic, which modifies the microstructure of lipid rafts. It can sequester cholesterol present on the cell membrane of eukaryotes. Nystatin regulates immune responses through cytokine signaling, lymphocyte activation and pathogen recognition.

Atenção

This product is stable at 37°C for three days.

Nota de preparo

It is 0.1μ filtered and cell culture tested.

Outras notas

Nystatin suspension available in 20 mL and 100 mL pack size.
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable