M7765

1-Oleoyl-rac-glycerol

≥99%

• Sinônimo(s): MG(18:1(9Z)/0:0/0:0)[rac], 1-(cis-9-Octadecenoyl)-rac-glycerol, rac-Glycerol 1-monooleate, DL-α-Monoolein, Glyceryl cis-9-octadecenoate, Monoolein
• Fórmula linear: CH₃(CH₂)₇CH=CH(CH₂)₇COOCH₂CHOHCH₂OH
• Número CAS: 111-03-5
• Peso molecular: 356.54
• Beilstein: 1728976
• Número CE: 203-827-7
• Número MDL: MFCD00042735
• Código UNSPSC: 12352211
• ID de substância PubChem: 24897178
• NACRES: NA.25

Propriedades

• fonte biológica: synthetic (organic)
• descrição: non-ionic
• Ensaio: ≥99%
• Formulário: powder
• pf: 35 °C
• grupo funcional: ester
• tipo de lipídio: neutral glycerides
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: O=C(CCCCCCC/C=C\CCCCCCCC)OCC(O)CO
• InChI: 1S/C21H40O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(24)25-19-20(23)18-22/h9-10,20,22-23H,2-8,11-19H2,1H3/b10-9-
• chave InChI: RZRNAYUHWVFMIP-KTKRTIGZSA-N

Descrição

Descrição geral

1-Oleoyl-rac-glycerol is a monoglyceride, obtained from natural oils and fats. It contains two alcohol groups that are reactive. It is soluble in chloroform and hexane. It can be crystallized from hexane.

Aplicação

1-Oleoyl-rac-glycerol has been used:

• to mix with the sample by two-syringe method, to achieve lipidic cubic phase in crystallization technique
• as a substrate for monoglyceride (MG) lipase assay
• in the preparation of MG solution for the measurement of in vitro MG hydrolase activity

Ações bioquímicas/fisiológicas

1-Oleoyl-rac-glycerol shows both inhibition and anti-inhibition action on the lipoprotein lipase mediated triglyceride hydrolysis.

Monoolein (1-Oleoyl-rac-glycerol) is used in the development of monoolein-based nanoparticulate liquid dispersions as possible vehicles for drug delivery.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 1
• Ponto de fulgor (°F): 309.2 °F - closed cup
• Ponto de fulgor (°C): 154.0 °C - closed cup
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)