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M1778

Sigma-Aldrich

Mucina

Type III, bound sialic acid 0.5-1.5 %, partially purified powder

Sinônimo(s):

MUC

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About This Item

Número CAS:
84082-64-4
Número CE:
282-010-7
Número MDL:
MFCD00131629
Código UNSPSC:
12352202
NACRES:
NA.61

fonte biológica

Porcine stomach

tipo

Type III

forma

partially purified powder

composição

bound sialic acid, 0.5-1.5%

técnica(s)

microbiological culture: suitable

solubilidade

NaOH: soluble 20 mg/mL

temperatura de armazenamento

2-8°C

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Descrição geral

Mucins or mucus glycoproteins are the main macromolecular components of mammalian mucus. It was also used in a study to evaluate the sputum smears concentrated by cyto-centrifugation for detection of acid-fast bacilli.

Aplicação

Mucin from porcine stomach was used in studies on the binding site of the galactose-specific agglutinin PA-IL from Pseudomonas aeruginosa.

Ações bioquímicas/fisiológicas

Mucus forms the protective cover for all epithelial surfaces. The major structural component of mucus is gel-forming mucins. The mucus layer covering the intestinal epithelium has the MUC2 mucin as its central molecule. MUC2 is produced by goblet cells.

Nota de preparo

Prepared according to the method of Glenister, et al., for use in complex growth media for dental plaque bacteria.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

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Applied and environmental microbiology, 74(15), 4847-4852 (2008-06-10)
The metabolism of isoflavones by gut bacteria plays a key role in the availability and bioactivation of these compounds in the intestine. Daidzein and genistein are the most common dietary soy isoflavones. While daidzein conversion yielding equol has been known
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The Burkholderia cepacia complex (Bcc) species are important opportunistic pathogens with intrinsic antibiotic resistance. They are also well known as contaminants of disinfectants, yet their biocide susceptibility has not been studied in detail. We investigated Bcc biocide susceptibility and correlated
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mBio, 10(6) (2019-11-21)
Metazoans were proposed to host bacteriophages on their mucosal surfaces in a symbiotic relationship, where phages provide an external immunity against bacterial infections and the metazoans provide phages a medium for interacting with bacteria. However, scarce empirical evidence and model
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Microbiome, 8(1), 33-33 (2020-03-13)
Human-targeted drugs may exert off-target effects or can be repurposed to modulate the gut microbiota. However, our understanding of such effects is limited due to a lack of rapid and scalable assay to comprehensively assess microbiome responses to drugs. Drugs
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Journal of pharmacological and toxicological methods, 53(2), 160-167 (2006-03-02)
A method to measure the mucin concentration in bronchoalveolar lavage (BAL) fluid was developed to aid efforts to identify pharmacologically the mechanisms that modulate pathophysiological mucin secretion. Mucins are the major macromolecular components of mucus. In the airways, mucus is
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