H7250

Histamine dihydrochloride

≥99% (TLC), powder, endogenous histamine receptor agonist

• Sinônimo(s): 2-(4-Imidazolyl)ethylamine dihydrochloride
• Fórmula empírica (Notação de Hill): C₅H₉N₃ · 2HCl
• Número CAS: 56-92-8
• Peso molecular: 184.07
• Beilstein: 3624116
• Número CE: 200-298-4
• Número MDL: MFCD00012703
• Código UNSPSC: 12352116
• eCl@ss: 32160406
• ID de substância PubChem: 24277777
• NACRES: NA.77

Propriedades

• Nome do produto: Histamine dihydrochloride, ≥99% (TLC), powder
• Nível de qualidade: 200
• Ensaio: ≥99% (TLC)
• Formulário: powder
• cor: white to off-white
• pf: 249-252 °C (lit.)
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: Cl[H].Cl[H].NCCc1c[nH]cn1
• InChI: 1S/C5H9N3.2ClH/c6-2-1-5-3-7-4-8-5;;/h3-4H,1-2,6H2,(H,7,8);2*1H
• chave InChI: PPZMYIBUHIPZOS-UHFFFAOYSA-N
• Informações sobre genes: human ... HRH1(3269) , HRH2(3274)

Descrição

Descrição geral

Histamine dihydrochloride is a derivative of histamine. It prevents the formation of ROS (reactive oxygen species), which inhibits the activation of T cells and natural killer cells. Histamine dihydrochloride is implicated in tumor cell apoptosis. It prevents the relapse of acute myeloid leukemia in patients.

Aplicação

Histamine dihydrochloride has been used:

• as a orthograde cotransmitter in producing excitatory postsynaptic potential (EPSP)
• to determine its level in fish using HPLC (high performance liquid chromatography)
• to assess the tracheal response to antigens in guinea-pigs

Características e benefícios

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Informações de segurança

• Pictogramas: GHS08,GHS07
• Palavra indicadora: Danger
• Frases de perigo: H315,H317,H319,H334,H335
• Declarações de precaução: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Classificações de perigo: Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Órgãos-alvo: Respiratory system
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Faceshields, Gloves