H3536
Haptoglobin from pooled human plasma
≥95% (SDS-PAGE), lyophilized powder
Sinônimo(s):
Haptoglobin from human plasma
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About This Item
Produtos recomendados
fonte biológica
human plasma (pooled)
Nível de qualidade
Ensaio
≥95% (SDS-PAGE)
Formulário
lyophilized powder
técnica(s)
activity assay: suitable
solubilidade
H2O: soluble 10 mg/mL
nº de adesão UniProt
temperatura de armazenamento
−20°C
Informações sobre genes
human ... HP(3240)
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Descrição geral
Haptoglobin is an α2-globulin found in normal plasma at a concentration of 82-236 mg/dl and accounts for 0.4-2.6% of the total plasma proteins.The monomeric form of this acute phase plasma protein is composed of four polypeptide chains: two α chains and two β chains.
Haptoglobin is an acute phase protein that scavenges hemoglobin released into the circulation. Haptoglobin, the plasma protein with highest binding affinity to hemoglobin, is mainly expressed in the liver.
Aplicação
Haptoglobin was used to study induction of the acrosome reaction in sperm. Exposure to low temperature increases their rate of fusion with zona-free hamster oocytes.
Ações bioquímicas/fisiológicas
Functions by binding to plasma hemoglobin (from hemolysis). The complex is removed from the circulation, by binding to CD163 receptors on macrophages, to salvage iron and prevent oxidative damage.
Outras notas
Occurs as 3 major phenotypes: type 1-1, type 2-1, type 2-2.
Exoneração de responsabilidade
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
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