SRP6506

Haptoglobin Plasma (MixedType) from human plasma

≥95% (SDS-PAGE)

• Sinônimo(s): Bp, Haptoglobin b-Chain, Hp, haptoglobin a-chain
• Código UNSPSC: 12352202
• NACRES: NA.32

Propriedades

• fonte biológica: human plasma
• Ensaio: ≥95% (SDS-PAGE)
• Formulário: lyophilized
• peso molecular: monomer 200 kDa (Hp 2-1); monomer 400 kDa (Hp 2-2); monomer 86 kDa (Hp 1-1)
• embalagem: pkg of 1 mg
• nº de adesão UniProt: P00738
• Condições de expedição: wet ice
• temperatura de armazenamento: −20°C
• Informações sobre genes: human ... HP(3240)

Descrição

Descrição geral

An acute-phase plasma protein found in human plasma at 100-300 mg/100 mL. Binds hemoglobin, thus preventing loss of iron through the kidneys. Humans are polymorphic for haptoglobin, with three major phenotypes: Hp 1-1, Hp 2-1, and Hp 2-2. While the phenotypic distribution can vary greatly between ethnicities and geographic location, the Hp 2-1 phenotype is the most prevalent phenotype in humans. Plasma concentrations of haptoglobin are highest in individuals with Hp 1-1, intermediate in Hp 2-1 individuals, and lowest in Hp 2-2 individuals. Hp 1-1 is the most effective at binding hemoglobin, and Hp 2-2 is the least effective. This functional difference may be associated with the frequency and severity of epilepsy attacks, as researchers have found a correlation between recurring seizures and the Hp 2-2 phenotype.

forma física

Lyophilized as a salt-free solid.

Informações de segurança

• Código de classe de armazenamento: 13 - Non Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable