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Documentos Principais

G5509

Sigma-Aldrich

D-Glucosamine 6-phosphate

≥98% (TLC)

Sinônimo(s):

2-Amino-2-deoxyglucose 6-phosphate

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About This Item

Fórmula empírica (Notação de Hill):
C6H14NO8P
Número CAS:
Peso molecular:
259.15
Número MDL:
Código UNSPSC:
12352201
ID de substância PubChem:
NACRES:
NA.25

fonte biológica

natural (inorganic)

Nível de qualidade

Ensaio

≥98% (TLC)

Formulário

powder

técnica(s)

thin layer chromatography (TLC): suitable

Impurezas

≤10% water (Karl Fischer)

cor

white

solubilidade

water: 50 mg/mL, clear to hazy, colorless to almost colorless

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

NC(C=O)C(O)C(O)C(O)COP(O)(O)=O

InChI

1S/C6H14NO8P/c7-3(1-8)5(10)6(11)4(9)2-15-16(12,13)14/h1,3-6,9-11H,2,7H2,(H2,12,13,14)

chave InChI

AEJSSXDYDSUOOZ-UHFFFAOYSA-N

Descrição geral

D-Glucosamine 6-phosphate, the natural form of glucosamine, is a monosaccharide produced during hexosamine biosynthesis pathway by the enzyme glucosamine-6-phosphate deaminase from the two substrates fructose 6-phosphate and glutamine.

Ligação

Stability is greater than that of the sodium salt.

Outras notas

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


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Stanislav S Terekhov et al.
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Microbial communities are self-controlled by repertoires of lethal agents, the antibiotics. In their turn, these antibiotics are regulated by bioscavengers that are selected in the course of evolution. Kinase-mediated phosphorylation represents one of the general strategies for the emergence of
James S Davies et al.
FEBS letters, 593(1), 52-66 (2018-11-10)
N-Acetylglucosamine-6-phosphate deacetylase (NagA) and glucosamine-6-phosphate deaminase (NagB) are branch point enzymes that direct amino sugars into different pathways. For Staphylococcus aureus NagA, analytical ultracentrifugation and small-angle X-ray scattering data demonstrate that it is an asymmetric dimer in solution. Initial rate experiments
Reflections on glycobiology.
S Roseman
The Journal of biological chemistry, 276(45), 41527-41542 (2001-09-13)
Christina E Lünse et al.
ACS chemical biology, 6(7), 675-678 (2011-04-14)
The glmS-riboswitch is unique among riboswitch families as it represents a metabolite-dependent ribozyme that undergoes self-cleavage upon recognition of glucosamin-6-phosphate. The glmS-riboswitch is located in the 5'-untranslated region of bacterial genes involved in cell wall biosynthesis. Therefore, this riboswitch represents
Phillip J McCown et al.
RNA (New York, N.Y.), 17(4), 728-736 (2011-03-04)
Self-cleaving glmS ribozymes selectively bind glucosamine-6-phosphate (GlcN6P) and use this metabolite as a cofactor to promote self-cleavage by internal phosphoester transfer. Representatives of the glmS ribozyme class are found in Gram-positive bacteria where they reside in the 5' untranslated regions

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