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Key Documents

G5386

Sigma-Aldrich

Gly-Gly-Tyr-Arg

powder, ≥97% (HPLC)

Sinônimo(s):

GGYR, Glycyl-glycyl-tyrosyl-arginine

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About This Item

Fórmula empírica (Notação de Hill):
C19H29N7O6
Número CAS:
Peso molecular:
451.48
Número MDL:
Código UNSPSC:
12352204
ID de substância PubChem:
NACRES:
NA.83

product name

Gly-Gly-Tyr-Arg, ≥97% (HPLC)

fonte biológica

synthetic (organic)

Ensaio

≥97% (HPLC)

forma

powder

solubilidade

water: 2 mg/mL, clear, colorless

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

NCC(=O)NCC(=O)NC(Cc1ccc(O)cc1)C(=O)NC(CCCNC(N)=N)C(O)=O

InChI

1S/C19H29N7O6/c20-9-15(28)24-10-16(29)25-14(8-11-3-5-12(27)6-4-11)17(30)26-13(18(31)32)2-1-7-23-19(21)22/h3-6,13-14,27H,1-2,7-10,20H2,(H,24,28)(H,25,29)(H,26,30)(H,31,32)(H4,21,22,23)

chave InChI

FJPHHBGPPJXISY-UHFFFAOYSA-N

Aplicação

Gly-Gly-Tyr-Arg has been used:
  • in the synthesis of the dimethoxyphosphotyrosine adduct to determine if diethoxyphosphate tyrosine (depY), a monoclonal antibody could distinguish between dimethoxyphosphotyrosine and diethoxyphosphotyrosine
  • to graft on to a soft polyacrylamide for sodium dodecyl sulfate–polyacrylamide gel electrophoresis (SDS-PAGE) to perform high-resolution separation of peptides
  • as a model peptide to react with 3,3-dithiobis(sulfosuccinimidyl propionate) (DTSSP) to understand the chemistry of DTSSP and similar cross-linking reagents

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


Certificados de análise (COA)

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Soy peptide solution (40%, w/w) was successfully encapsulated in a W1/O/W2 double emulsion produced by a two-step emulsification process. Polyglycerol polyricinoleate (PGPR) was found to be an effective inner emulsifier compared to Span 60 and lecithin to produce stable W1/O
N Belcheva et al.
Journal of biomaterials science. Polymer edition, 9(3), 207-226 (1998-04-29)
A new synthetic approach has been applied to obtain novel di-, tetra-, and (multi)-peptide containing polymer conjugates in quantitative yields with a high degree of conjugation. Bis-(N-hydroxysuccinimidyl) esters of PEG (Mw = 200, 600, 1400, 2000, and 3400) were synthesized
A J Kettle
FEBS letters, 379(1), 103-106 (1996-01-22)
Hypochlorous acid chlorinates tyrosyl residues in small peptides to produce chlorotyrosine. Detection of chlorotyrosine has the potential to unequivocally identify the contribution hypochlorous acid makes to inflammation. I have developed a selective and sensitive HPLC assay for measuring chlorotyrosine. When
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Journal of the American Society for Mass Spectrometry, 15(5), 736-749 (2004-05-04)
Synthetic cross-linking reagents, such as 3,3'-dithiobis(sulfosuccinimidyl propionate), DTSSP, can react with sidechains of amino acids that are within close proximity. Identification of cross-linked residues provides insight into the folded structures of proteins. However, analysis of proteolytic digests of proteins cross-linked
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BMC microbiology, 12, 199-199 (2012-09-12)
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