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Documentos Principais

G1377

Sigma-Aldrich

Gly-Gly-Gly

≥98% (TLC)

Sinônimo(s):

Glycyl-glycyl-glycine, Triglycine

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About This Item

Fórmula linear:
NH2CH2CONHCH2CONHCH2COOH
Número CAS:
Peso molecular:
189.17
Beilstein:
1711130
Número CE:
Número MDL:
Código UNSPSC:
12352209
ID de substância PubChem:
NACRES:
NA.26

Nome do produto

Gly-Gly-Gly,

Ensaio

≥98% (TLC)

Nível de qualidade

Formulário

powder

cor

white

aplicação(ões)

peptide synthesis

cadeia de caracteres SMILES

NCC(=O)NCC(=O)NCC(O)=O

InChI

1S/C6H11N3O4/c7-1-4(10)8-2-5(11)9-3-6(12)13/h1-3,7H2,(H,8,10)(H,9,11)(H,12,13)

chave InChI

XKUKSGPZAADMRA-UHFFFAOYSA-N

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Amino Acid Sequence

Gly-Gly-Gly

Aplicação

Triglycine (Gly-Gly-Gly) is used as a model peptide for studies of physicochemical parameters and molecular associations of small peptides. Triglycine is used as a copper chelator.

Ações bioquímicas/fisiológicas

Substrate for reproducible serum protein measurements by the biuret reaction and for the assay of aminotripeptidases.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)


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Certificados de análise (COA)

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Gly-Gly BioPerformance Certified, suitable for cell culture, ≥99%

Sigma-Aldrich

G3915

Gly-Gly

Gly-Tyr

Sigma-Aldrich

G3502

Gly-Tyr

GlycylGlycine

SAFC

G0674

GlycylGlycine

Blake E Ziegler et al.
The journal of physical chemistry. A, 114(44), 11953-11963 (2010-10-26)
Hydrogen/deuterium exchange reactions involving protonated triglycine and deuterated ammonia (ND(3)) have been examined in the gas phase using a Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometer. Ab initio and density functional theory (DFT) calculations have been carried out to
S J Woltman et al.
Analytical chemistry, 67(3), 541-551 (1995-02-01)
The reversible electrochemistry of the Cu(II)/Cu(III) couple was investigated for the copper(II) complexes of triglycine (G3), tetraglycine (G4), and pentaglycine (G5) in alkaline solution using a rotating ring-disk electrode (RRDE). The study was motivated by the need to elucidate electrochemical
Jiyun Shi et al.
Bioconjugate chemistry, 20(4), 750-759 (2009-03-27)
Radiolabeled cyclic RGD (Arg-Gly-Asp) peptides represent a new class of radiotracers with potential for early tumor detection and noninvasive monitoring of tumor metastasis and therapeutic response in cancer patients. This article describes the synthesis of two cyclic RGD peptide dimer
Angelo Bella et al.
Angewandte Chemie (International ed. in English), 51(2), 428-431 (2011-11-25)
Two faces for one matrix: A single bifaceted cyclopeptide block forms highly branched, porous, and intricate fibrillar networks, which span microscopic dimensions and mimic the extracellular matrix to support cell growth and proliferation. The peptide block has two domains connected
Jiyun Shi et al.
Journal of medicinal chemistry, 51(24), 7980-7990 (2008-12-04)
This report describes the synthesis of two new cyclic RGD (Arg-Gly-Asp) dimers, 3 (E[G(3)-c(RGDfK)](2)) and 4 (G(3)-E[G(3)-c(RGDfK)](2)), and their corresponding conjugates 5 (HYNIC-E[G(3)-c(RGDfK)](2): HYNIC = 6-(2-(2-sulfonatobenzaldehyde)hydrazono)nicotinyl) and 6 (HYNIC-G(3)-E[G(3)-c(RGDfK)](2)). Integrin alpha(v)beta(3) binding affinities of 5 and 6 were determined by

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