F8384

Flavin adenine dinucleotide disodium salt hydrate

BioReagent, suitable for cell culture

• Sinônimo(s): FAD, FAD-Na₂, Riboflavin 5′-adenosine diphosphate disodium salt
• Fórmula empírica (Notação de Hill): C₂₇H₃₁N₉Na₂O₁₅P₂ · xH₂O
• Número CAS: 84366-81-4
• Peso molecular: 829.51 (anhydrous basis)
• Beilstein: 5326842
• Número MDL: MFCD08277021
• Código UNSPSC: 12352207
• ID de substância PubChem: 24894962
• NACRES: NA.75

Propriedades

• fonte biológica: bovine milk
• linha de produto: BioReagent
• Ensaio: ≥95%
• forma: powder
• técnica(s): cell culture | mammalian: suitable
• solubilidade: water: 50 mg/mL, clear
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: [Na+].[Na+].[H]O[H].Cc1cc2N=C3C(=O)NC(=O)N=C3N(C[C@H](O)[C@H](O)[C@H](O)COP([O-])(=O)OP([O-])(=O)OC[C@H]4O[C@H]([C@H](O)[C@@H]4O)n5cnc6c(N)ncnc56)c2cc1C
• InChI: 1S/C27H33N9O15P2.2Na.H2O/c1-10-3-12-13(4-11(10)2)35(24-18(32-12)25(42)34-27(43)33-24)5-14(37)19(39)15(38)6-48-52(44,45)51-53(46,47)49-7-16-20(40)21(41)26(50-16)36-9-31-17-22(28)29-8-30-23(17)36;;;/h3-4,8-9,14-16,19-21,26,37-41H,5-7H2,1-2H3,(H,44,45)(H,46,47)(H2,28,29,30)(H,34,42,43);;;1H2/q;2*+1;/p-2/t14-,15+,16+,19-,20+,21+,26+;;;/m0.../s1
• chave InChI: GXTPHHZYFMAGLX-UJXBNFGUSA-L

Descrição

Descrição geral

Flavin adenine dinucleotide (FAD) is a redox cofactor of flavoproteins, such as cytochrome-b₅ reductase enzyme. With the help of nicotinamide adenine dinucleotide phosphate (NADPH), FAD can be reduced to form FADH₂.

Aplicação

Flavin adenine dinucleotide (FAD) is used as a redox cofactor (electron carrier) by flavoproteins including succinate dehydrogenase (complex), α-ketoglutarate dehydrogenase, apoptosis-inducing factor 2 (AIF-M2, AMID), folate/FAD-dependent tRNA methyltransferases, and N-hydroxylating flavoprotein monooxygenases. FAD is a component of the pyruvate dehydrogenase complex.

Flavin adenine dinucleotide disodium salt hydrate has been used as a component in the extraction buffer for plant tissue extraction. It has also been used to study its effects on infarct areas of middle cerebral artery occlusion (MCAO) induced mice.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)