F5178

Flavin-Containing Monooxygenase-5, Microsomes human

recombinant, expressed in baculovirus infected insect cells, buffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer)

• Sinônimo(s): FMO-5
• Número da licença da enzima: 1.14.13.8 (BRENDA, IUBMB)
• Código UNSPSC: 12352204
• NACRES: NA.54

Propriedades

• recombinante: expressed in baculovirus infected insect cells
• Nível de qualidade: 200
• Formulário: buffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer)
• atividade específica: ≥700 units/mg protein
• peso molecular: 55-60 kDa
• embalagem: vial of 2.5 mg
• nº de adesão UniProt: P49326
• Condições de expedição: dry ice
• temperatura de armazenamento: −70°C
• Informações sobre genes: human ... FMO5(2330)

Descrição

Aplicação

FMO5 is the only FMO isoform expressed in both adult and fetal human liver.

Ações bioquímicas/fisiológicas

FMO′s are responsible for catalyzing the oxygenation of a variety of xenobiotic and drug compounds including environmental pollutants and carcinogens, which demonstrate a nucleophilic nitrogen, sulfur, selenium, and phosphorous-containing moiety associated with their respective oxides. These enzymes are classified as Phase I or oxidative drug metabolism enzymes. FMO5 is the only FMO isoform expressed in both adult and fetal human liver.

Definição da unidade

methyl p-tolyl sulfide oxidase activity: One unit will catalyze the production of 1.0 picomole of methyl p-tolyl sulfoxide.

forma física

Solution in 100 mM potassium phosphate buffer, pH 7.4.

Informações de segurança

• Código de classe de armazenamento: 10 - Combustible liquids
• Classe de risco de água (WGK): WGK 2
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)