D8668

2′-Deoxyadenosine monohydrate

powder, BioReagent, suitable for cell culture

• Sinônimo(s): 9-(2-Deoxy-β-D-ribofuranosyl)adenine, Adenine deoxyriboside
• Fórmula empírica (Notação de Hill): C₁₀H₁₃N₅O₃ · H₂O
• Número CAS: 16373-93-6
• Peso molecular: 269.26
• Beilstein: 91015
• Número CE: 213-488-7
• Número MDL: MFCD00005754
• Código UNSPSC: 12352207
• ID de substância PubChem: 24894112
• NACRES: NA.75

Propriedades

• fonte biológica: synthetic (organic)
• Nível de qualidade: 200
• linha de produto: BioReagent
• Ensaio: ≥99% (HPLC)
• forma: powder
• técnica(s): cell culture | mammalian: suitable
• solubilidade: H₂O: soluble 25 mg/mL, clear to slightly hazy, colorless to faintly yellow
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: [H]O[H].Nc1ncnc2n(cnc12)[C@H]3C[C@H](O)[C@@H](CO)O3
• InChI: 1S/C10H13N5O3/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(17)6(2-16)18-7/h3-7,16-17H,1-2H2,(H2,11,12,13)/t5-,6+,7+/m0/s1
• chave InChI: OLXZPDWKRNYJJZ-RRKCRQDMSA-N

Descrição

Aplicação

2′-Deoxyadenosine monohydrate has been used as a nucleotide precursor:

• To study the importance of homologous recombination at the interface between replication and mitosis
• To analyze deoxynucleoside-assisted transductions
• To study the effect of increased deoxycytidine on gemcitabine resistance in pancreatic cancer cells

2′-Deoxyadenosine monohydrate has been used for the preparation of deoxyribonucleoside stock solution for the anaerobic culture of Bacillus mojavensis strains including JF-2 and two Bacillus subtilis strains.

Ações bioquímicas/fisiológicas

Excess 2′-deoxyadenosine gets converted to adenosine triphosphate (dATP), which inhibits ribonucleotide reductase.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Faceshields, Gloves