C4407
Human Collagen Type III
from human placenta, powder, suitable for cell culture
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About This Item
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Nome do produto
Colágeno, Bornstein and Traub Type III (Sigma Type X), powder
fonte biológica
human placenta
Nível de qualidade
Ensaio
≥90% (GE)
Formulário
powder
técnica(s)
cell culture | mammalian: suitable
Impurezas
HIV, hepatitis B and hepatitis C, none detected
solubilidade
aqueous acid: soluble
nº de adesão UniProt
temperatura de armazenamento
2-8°C
Informações sobre genes
human ... COL3A1(1300)
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Aplicação
Collagen from human placenta has been used to assess the bioelectric effects of quinine on airway epithelial cells, to study the selective toxicity of engineered lentvirus lytic peptides and in a particle aggregation assay for the rapid detection of fibronectin, fibrinogen and collagen receptors on Staphylococcus aureus. It has also been used in a magnesium-dependent, collagen-binding assay during characterization of human lung tumor-associated antigens.
Componentes
All collagen molecules are composed of three polypeptide chains arranged in a triple helical conformation, with a primary structure that is mostly a repeating motif with glycine in every third position and proline or 4-hydroxyproline frequently preceding the glycine residue.
Atenção
This product should be stored at 2-8 °C and will retain activity in these conditions for 2 years.
Nota de preparo
This product was prepared by a modification of the pepsin extraction and salt fractionation method of Hill, R.J. and Harper, E., Anal. Biochem., 141 (1984). It is a lyophilized powder that can be reconstituted in sterile .5 M acetic acid, PBS or water at 1 mg/mL. A PBS solution will be stable for at least one year at -20°C.
Nota de análise
An SDS polyacrylamide gel electrophoresis test run under reducing conditions consistent with basement membrane collagen yields three major bands.
Outras notas
O colágeno é classificado em diversos tipos estrutural e geneticamente distintos. Usamos a nomenclatura proposta por Bornstein e Traub. Tome cuidado para não confundir as designações de tipos da Sigma com tipos de classificação de colágenos reconhecidos.
Código de classe de armazenamento
11 - Combustible Solids
Classe de risco de água (WGK)
WGK 1
Ponto de fulgor (°F)
Not applicable
Ponto de fulgor (°C)
Not applicable
Equipamento de proteção individual
Eyeshields, Gloves, type N95 (US)
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