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Documentos Principais

B8061

Sigma-Aldrich

N-Butyl-N-(4-hydroxybutyl)nitrosamine

ISOPAC®, ≥90% (GC)

Sinônimo(s):

BBN, N-Butyl-N-butan-4-ol-nitrosamine, N-Butyl-N-nitroso-4-aminobutanol, OH-BBN

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About This Item

Fórmula empírica (Notação de Hill):
C8H18N2O2
Número CAS:
Peso molecular:
174.24
Código UNSPSC:
12352116
NACRES:
NA.25

Nível de qualidade

Ensaio

≥90% (GC)

Formulário

liquid

temperatura de armazenamento

2-8°C

InChI

1S/C8H18N2O2/c1-2-3-6-10(9-12)7-4-5-8-11/h11H,2-8H2,1H3

chave InChI

DIKPQFXYECAYPC-UHFFFAOYSA-N

Aplicação

N-Butyl-N-(4-hydroxybutyl)nitrosamine (BBN), a carcinogen, is used to induce histiologically relevant aggressive urinary bladder cancer in animal models.

Ações bioquímicas/fisiológicas

Carcinogen used to induce urinary bladder cancer in animal models. The result of exposure is histologically comparable to human urinary bladder tumorigenesis. Used in chemopreventative studies.

Embalagem

Packaged in a 100 mL serum bottle with butyl rubber stopper and aluminum tear seal.

Atenção

Injecting any compatible solvent permits preparation of any desired strength solution without exposure.

Reconstituição

Dissolving the contents in 100 mL of solvent yields a 1% solution.

Informações legais

Isopac is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictogramas

Health hazardExclamation mark

Palavra indicadora

Danger

Frases de perigo

Classificações de perigo

Acute Tox. 4 Oral - Carc. 1B

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

296.6 °F

Ponto de fulgor (°C)

147 °C

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter


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Sigma-Aldrich

T5648

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The potential promoting effect of Diuron was investigated in a mouse model of mammary and urinary bladder carcinogenesis induced by 7,12-dimethylbenz(a)anthracene (DMBA) and N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN). Four-week old female Swiss mice were allocated to five groups: Groups G1-G3 received DMBA (5
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