B8061
N-Butyl-N-(4-hydroxybutyl)nitrosamine
ISOPAC®, ≥90% (GC)
Sinônimo(s):
BBN, N-Butyl-N-butan-4-ol-nitrosamine, N-Butyl-N-nitroso-4-aminobutanol, OH-BBN
Faça loginpara ver os preços organizacionais e de contrato
About This Item
Produtos recomendados
Nível de qualidade
Ensaio
≥90% (GC)
Formulário
liquid
temperatura de armazenamento
2-8°C
InChI
1S/C8H18N2O2/c1-2-3-6-10(9-12)7-4-5-8-11/h11H,2-8H2,1H3
chave InChI
DIKPQFXYECAYPC-UHFFFAOYSA-N
Aplicação
N-Butyl-N-(4-hydroxybutyl)nitrosamine (BBN), a carcinogen, is used to induce histiologically relevant aggressive urinary bladder cancer in animal models.
Ações bioquímicas/fisiológicas
Carcinogen used to induce urinary bladder cancer in animal models. The result of exposure is histologically comparable to human urinary bladder tumorigenesis. Used in chemopreventative studies.
Embalagem
Packaged in a 100 mL serum bottle with butyl rubber stopper and aluminum tear seal.
Atenção
Injecting any compatible solvent permits preparation of any desired strength solution without exposure.
Reconstituição
Dissolving the contents in 100 mL of solvent yields a 1% solution.
Informações legais
Isopac is a registered trademark of Merck KGaA, Darmstadt, Germany
Palavra indicadora
Danger
Frases de perigo
Declarações de precaução
Classificações de perigo
Acute Tox. 4 Oral - Carc. 1B
Código de classe de armazenamento
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
Classe de risco de água (WGK)
WGK 3
Ponto de fulgor (°F)
296.6 °F
Ponto de fulgor (°C)
147 °C
Equipamento de proteção individual
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Escolha uma das versões mais recentes:
Já possui este produto?
Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.
Os clientes também visualizaram
Cancer prevention research (Philadelphia, Pa.), 2(11), 951-956 (2009-11-07)
Nonsteroidal anti-inflammatory drugs (NSAID) have been highly effective in preventing colon, urinary bladder, and skin cancer preclinically, and also in clinical trials of colon adenoma formation. However, certain NSAIDs cause gastrointestinal ulceration and may increase cardiovascular events. Naproxen seems to
Inhibition of bladder tumor growth by chitooligosaccharides in an experimental carcinogenesis model.
Marine drugs, 10(12), 2661-2675 (2013-01-25)
Urinary bladder cancer is one of the most common cancers worldwide, with the highest incidence in industrialized countries. Patients with cancer commonly use unconventional and complementary therapy including nutraceuticals. In this study we evaluated the efficacy of chitooligosaccharides (in orange
Cancer epidemiology, 34(3), 350-354 (2010-04-07)
Green tea polyphenol (GTP) suppresses malignancy in bladder cancer cell lines. However, the detail of its anti-carcinogenic effect in vivo is not fully understood. This study investigated the effect of GTP on bladder tumor size and angiogenesis in mice given
Archives of toxicology, 84(2), 165-173 (2009-11-11)
The potential promoting effect of Diuron was investigated in a mouse model of mammary and urinary bladder carcinogenesis induced by 7,12-dimethylbenz(a)anthracene (DMBA) and N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN). Four-week old female Swiss mice were allocated to five groups: Groups G1-G3 received DMBA (5
Journal of ethnopharmacology, 135(1), 162-172 (2011-03-15)
Extracts of Paeonia lactiflora Pall (RPA), a traditional Chinese medicines has been shown to treat cancers. The purpose of this study is to evaluate the anticancer effect of RPA in urinary bladder carcinoma in vitro and in vivo. The cell
Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.
Entre em contato com a assistência técnica