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B6936

Sigma-Aldrich

3-Benzidino-6-(4-chlorophenyl)pyridazine

≥98% (HPLC), solid

Sinônimo(s):

BCP

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About This Item

Fórmula empírica (Notação de Hill):
C22H17N4Cl
Número CAS:
901773-91-9
Peso molecular:
372.85
Número MDL:
MFCD11046030
Código UNSPSC:
12352202
ID de substância PubChem:
329773289
NACRES:
NA.77

Ensaio

≥98% (HPLC)

Formulário

solid

cor

light yellow

solubilidade

DMSO: >14 mg/mL

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

Nc1ccc(cc1)-c2ccc(Nc3ccc(nn3)-c4ccc(Cl)cc4)cc2

InChI

1S/C22H17ClN4/c23-18-7-1-17(2-8-18)21-13-14-22(27-26-21)25-20-11-5-16(6-12-20)15-3-9-19(24)10-4-15/h1-14H,24H2,(H,25,27)

chave InChI

ABGCSSPCKSVMHI-UHFFFAOYSA-N

Ações bioquímicas/fisiológicas

3-Benzidino-6-(4-chlorophenyl)pyridazine is an inhibitor of delayed rectifier and transient outward potassium currents. The IC50 values for the blocking action of BCP on IKDR and IKA was calculated as 7.13 μM and 0.55 μM, respectively in acutely isolated rat hippocampal pyramidal neurons by using whole-cell patch-clamp technique. The parent compound, minaprine (Cat. No. M3157), has selective affinity for M1 muscarinic receptors and possesses memory-enhancing properties and also acts as an antidepressant.

Características e benefícios

This compound is featured on the Potassium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Pictogramas

Skull and crossbones
GHS06

Palavra indicadora

Danger

Frases de perigo

H301

Declarações de precaução

P264 - P270 - P301 + P310 - P405 - P501

Classificações de perigo

Acute Tox. 3 Oral

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

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Certificados de análise (COA)

Lot/Batch Number
087K4602

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