B3313

Bicyclol

≥98% (HPLC)

• Sinônimo(s): 4, 4′-dimethoxy-2, 3, 2′, 3′-bis(methylenedioxy)-6-hydroxymethyl-6′-methoxy-carbonyl biphenyl
• Fórmula empírica (Notação de Hill): C₁₉H₁₈O₉
• Número CAS: 118159-48-1
• Peso molecular: 390.34
• Número MDL: MFCD00889471
• Código UNSPSC: 12352202
• ID de substância PubChem: 329773215
• NACRES: NA.77

Propriedades

• Nível de qualidade: 100
• Ensaio: ≥98% (HPLC)
• Formulário: powder
• condição de armazenamento: desiccated
• cor: white to off-white
• solubilidade: DMSO: >10 mg/mL
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: COC(=O)c1cc(OC)c2OCOc2c1-c3c(CO)cc(OC)c4OCOc34
• InChI: 1S/C19H18O9/c1-22-11-4-9(6-20)13(17-15(11)25-7-27-17)14-10(19(21)24-3)5-12(23-2)16-18(14)28-8-26-16/h4-5,20H,6-8H2,1-3H3
• chave InChI: KXMTXZACPVCDMH-UHFFFAOYSA-N

Descrição

Descrição geral

Bicyclol has anti-inflammatory properties and enhances the prognosis of kidney transplantation. It is involved in the removal of reactive oxygen species and modulates cytokine secretion.

Ações bioquímicas/fisiológicas

Bicyclol is a anti-hepatitis drug, used in China for chronic hepatitis B and presumably C.

Bicyclol is a anti-hepatitis drug, used in China for chronic hepatitis B and presumably C. The drug appears to protect against liver injury in animals. Recently it was reported that bicyclol induce the expression of hepatic HSP27 and HSP70, and thus consequently inhibits the transcription factor NF-?B-mediated apoptosis and necrosis in liver tissue. It appears that bicyclol induces hepatic HSP27 and HSP70 expression through activating transcription of HSPs genes.

Informações de segurança

• Pictogramas: GHS09
• Palavra indicadora: Warning
• Frases de perigo: H410
• Declarações de precaução: P273 - P391 - P501
• Classificações de perigo: Aquatic Acute 1 - Aquatic Chronic 1
• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: dust mask type N95 (US), Eyeshields, Gloves