A9376

Adenosine 2′:3′-cyclic monophosphate sodium salt

≥93%

• Sinônimo(s): 2′,3′-cAMP sodium salt
• Fórmula linear: C₁₀H₁₁N₅O₆PNa
• Número CAS: 37063-35-7
• Peso molecular: 351.19
• Número CE: 253-328-3
• Número MDL: MFCD00005757
• Código UNSPSC: 41106305
• eCl@ss: 32160414
• ID de substância PubChem: 24891439
• NACRES: NA.51

Propriedades

• fonte biológica: synthetic (organic)
• Nível de qualidade: 200
• Ensaio: ≥93%
• forma: powder
• solubilidade: water: 50 mg/mL, clear, colorless
• temperatura de armazenamento: −20°C
• cadeia de caracteres SMILES: [Na+].Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO)[C@H]4OP([O-])(=O)O[C@@H]34
• InChI: 1S/C10H12N5O6P.Na/c11-8-5-9(13-2-12-8)15(3-14-5)10-7-6(4(1-16)19-10)20-22(17,18)21-7;/h2-4,6-7,10,16H,1H2,(H,17,18)(H2,11,12,13);/q;+1/p-1/t4-,6-,7-,10-;/m1./s1
• chave InChI: VSDSIACSNXHGOV-MCDZGGTQSA-M

Descrição

Aplicação

Adenosine 2′:3′-cyclic monophosphate sodium salt has been used in lysis buffer for affinity purification and also in microscale thermophoresis measurements. It has also been used in electrophysiological studies of Tenebrio tubules.

Ações bioquímicas/fisiológicas

Adenosine 2′,3′-cyclic monophosphate (2′,3′-cAMP) is believed to serve as an extracellular source of adenosine. The release of extracellular 2′,3′-cAMP occurs in response to injury. 2′,3′-cAMP may be used to study the distribution and specificity of its degrading enzymes in the context of unique biological activities. 2′,3′-cAMP may also be used to study apoptosis induced at the level of mitochondrial permeability transition pores. 2′,3′-cAMP is converted into 2′-AMP and 3′-AMP which inhibit proliferation of preglomerular vascular smooth muscle cells and glomerular mesangial cells via A2B receptors.

Atenção

Caution: Do not confuse with the common adenosine 2′(3′)-monophosphate (mixed isomers).

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable