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89870

Sigma-Aldrich

Toluene 2,4-diisocyanate

purum, suitable for electron microscopy, ≥98.0% (GC)

Sinônimo(s):

2,4-Diisocyanatotoluene, 4-Methyl-m-phenylene diisocyanate, Tolylene 2,4-diisocyanate

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About This Item

Fórmula empírica (Notação de Hill):
C9H6N2O2
Número CAS:
584-84-9
Peso molecular:
174.16
Beilstein:
744602
Número CE:
209-544-5
Número MDL:
MFCD00002011
Código UNSPSC:
12352200
ID de substância PubChem:
57653363
NACRES:
NA.25

grau

purum

Nível de qualidade

200

Ensaio

≥98.0% (GC)

forma

liquid

técnica(s)

electron microscopy: suitable

índice de refração

n20/D 1.567

pb

124-126 °C/18 mmHg (lit.)
251 °C (lit.)

pf

19.5-21.5 °C (lit.)

densidade

1.21 g/mL at 20 °C
1.22 g/mL at 20 °C (lit.)

cadeia de caracteres SMILES

Cc1ccc(cc1N=C=O)N=C=O

InChI

1S/C9H6N2O2/c1-7-2-3-8(10-5-12)4-9(7)11-6-13/h2-4H,1H3

chave InChI

DVKJHBMWWAPEIU-UHFFFAOYSA-N

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Aplicação

Toluene 2,4-diisocyanate is used to study it occupational hazards (asthma, dermatitis) and mechanisms of action. Reagent for covalent protein crosslinking; For the immobilization of antibodies to a plastic surface for RIA

Outras notas

Reagent for covalent protein crosslinking; For the immobilization of antibodies to a plastic surface for RIA

Pictogramas

Skull and crossbonesHealth hazard
GHS06,GHS08

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 1 Inhalation - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

269.6 °F - closed cup

Ponto de fulgor (°C)

132 °C - closed cup

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

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Hexamethylene diisocyanate purum, ≥98.0% (GC)

Sigma-Aldrich

52650

Hexamethylene diisocyanate

T Saito et al.
Clinica chimica acta; international journal of clinical chemistry, 133(3), 301-310 (1983-10-14)
A novel procedure to fix antibody on a plastic surface was developed, using a polystyrene tube treated with 0.5% toluene 2,4-diisocyanate (TC) dissolved in carbon tetrachloride. Using 125I-labelled IgG, we found that the rate of immobilization of IgG was significantly
[57] Bifunctional reagents.
F Wold
Methods in enzymology, 25, 623-651 (1972-01-01)
Rahul Purwar et al.
Experimental dermatology, 20(9), 709-714 (2011-05-17)
Keratinocytes synthesize complement component 3 (C3) constitutively, and increased expression of C3 has been described during skin inflammation. In this study, we investigated the role of C3 in T cell-mediated allergic contact dermatitis, which is a clinical manifestation of contact
Olov Collste et al.
Journal of cardiac failure, 20(12), 968-972 (2014-10-01)
Our objective was to investigate whether dobutamine stress echocardiography (DSE) could induce abnormal cardiac function in takotsubo stress cardiomyopathy (TSC) patients in a stable condition after the acute attack. This was a case-control study and a substudy of the Stockholm
Tatiana Kuznetsova et al.
American journal of hypertension, 28(4), 535-545 (2014-09-23)
The cardio-renal interaction occurs via hemodynamic and humoral factors. Noninvasive assessment of renal hemodynamics is currently possible by assessment of renal resistive index (RRI) derived from intrarenal Doppler arterial waveforms as ((peak systolic velocity - end-diastolic velocity)/peak systolic velocity). Limited
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