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Merck
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Documentos Principais

90594

Supelco

Bisdemethoxycurcumin

analytical standard

Sinônimo(s):

(E,E)-1,7-Bis(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione, Bisdesmethoxycurcumin, Curcumin III, Didemethoxycurcumin

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About This Item

Fórmula empírica (Notação de Hill):
C19H16O4
Número CAS:
Peso molecular:
308.33
Beilstein:
3149384
Número MDL:
Código UNSPSC:
85151701
ID de substância PubChem:
NACRES:
NA.24

grau

analytical standard

Nível de qualidade

Ensaio

≥95.0% (HPLC)

prazo de validade

limited shelf life, expiry date on the label

técnica(s)

HPLC: suitable
gas chromatography (GC): suitable

aplicação(ões)

food and beverages

Formato

neat

cadeia de caracteres SMILES

Oc1ccc(cc1)\C=C\C(=O)CC(=O)\C=C\c2ccc(O)cc2

InChI

1S/C19H16O4/c20-16-7-1-14(2-8-16)5-11-18(22)13-19(23)12-6-15-3-9-17(21)10-4-15/h1-12,20-21H,13H2/b11-5+,12-6+

chave InChI

PREBVFJICNPEKM-YDWXAUTNSA-N

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Aplicação

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Embalagem

Bottomless glass bottle. Contents are inside inserted fused cone.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Certificados de análise (COA)

Lot/Batch Number

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Sigma-Aldrich

C1386

Curcumin

Tetrahydrocurcumin analytical standard

Supelco

50202

Tetrahydrocurcumin

Curcumin Pharmaceutical Secondary Standard; Certified Reference Material

Supelco

PHR2209

Curcumin

Jung Eun Kim et al.
Phytotherapy research : PTR, 17(5), 481-484 (2003-05-16)
Peroxynitrite is a cytotoxic intermediate produced by the reaction between the superoxide anion (O(2)) and nitric oxide (NO). The aim of this study was to investigate the scavenging effects of Curcuma longa L. on authentic peroxynitrite, and further studies are
Zhongfa Liu et al.
Bioorganic & medicinal chemistry letters, 19(3), 706-709 (2008-12-30)
Molecular docking of the interaction of curcumin and DNMT1 suggested that curcumin covalently blocks the catalytic thiolate of C1226 of DNMT1 to exert its inhibitory effect. This was validated by showing that curcumin inhibits the activity of M. SssI with
P V Leyon et al.
Journal of experimental & clinical cancer research : CR, 22(1), 77-83 (2003-05-03)
In this study, some of the synthetic curcuminoid derivatives are analyzed for their anti-angiogenic activity. Intraperitoneal administration of the compounds tetrahydrocurcumin (THC), salicyl curcumin (SC) and curcuminIII (C-III) reduced the number of tumour directed capillaries induced by injecting B16F-10 melanoma
W Chearwae et al.
Biochemical pharmacology, 68(10), 2043-2052 (2004-10-13)
P-glycoprotein (Pgp, ABCB1) is an ATP-dependent drug efflux pump linked to development of multidrug resistance (MDR) in cancer cells. Previously [Biochem Pharmacol 2002;64:573-82], we reported that a curcumin mixture could modulate both function and expression of Pgp. This study focuses
Ratheesh Mohan et al.
Journal of biochemical and molecular toxicology, e22315-e22315 (2019-02-23)
Alcoholic liver diseases are classified as one of the major reasons for worldwide morbidity and mortality. Curcuminoids exhibit a wide range of pharmacological activities that are beneficial for health, including hepatoprotective effects, but its clinical significance is limited due to

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