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Documentos Principais

239658

Supelco

Bisphenol A

≥99%

Sinônimo(s):

2,2-Bis(4-hydroxyphenyl)propane, 4,4′-Isopropylidenediphenol

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About This Item

Fórmula linear:
(CH3)2C(C6H4OH)2
Número CAS:
Peso molecular:
228.29
Beilstein:
1107700
Número CE:
Número MDL:
Código UNSPSC:
12000000
ID de substância PubChem:
NACRES:
NA.21

Ensaio

≥99%

Formulário

solid

p.e.

220 °C/4 mmHg (lit.)

pf

158-159 °C (lit.)

cadeia de caracteres SMILES

CC(C)(c1ccc(O)cc1)c2ccc(O)cc2

InChI

1S/C15H16O2/c1-15(2,11-3-7-13(16)8-4-11)12-5-9-14(17)10-6-12/h3-10,16-17H,1-2H3

chave InChI

IISBACLAFKSPIT-UHFFFAOYSA-N

Informações sobre genes

mouse ... Esr1(13982)
rat ... Ar(24208)

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Descrição geral

Bisphenol A (BPA) is a diphenylmethane derivative, commonly used in the production of polycarbonate plastics, epoxy resins, and various other plastic-based consumer products. It is also known to exhibit strong endocrine-disrupting ability.

Aplicação

The analytical standard can also be used as follows:
  • Quantitative analysis of bisphenol A and bisphenol S in three plastic product samples of a mineral water bottle, polycarbonate bottle, and baby bottle, using a modified glassy carbon electrode (GCE) sensor based on a crystalline covalent organic framework (COF)
  • Simultaneous determination of bisphenol A, S, and F in 112 samples of thermal paper receipts by liquid chromatography coupled to mass spectrometry (LC-MS) following their ultrasound-assisted extraction
  • Development and validation of a gas chromatography-tandem mass spectrometry (GC-MS/MS) method for the measurement of bisphenol A and 18 BPA-related compounds in 30 breast milk samples after their solid phase extraction (SPE)
  • Construction of an electrochemical sensor based on multi-walled carbon nanotubes (MWCNTs) modified glassy carbon electrode (GCE) for the determination of bisphenol A & S in river water and thermal paper samples by cyclic voltammetry (CV)
  • Determination of bisphenol A in urine samples using a novel method based on miniaturized QuEChERS extraction and gas chromatography-mass spectrometry (GC-MS)
  • Investigate the bisphenol A content from glass or Pasteur pipettes in biological liquids from maternal women using high-performance liquid chromatography (HPLC).

Palavra indicadora

Danger

Classificações de perigo

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Repr. 1B - Skin Sens. 1 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

440.6 °F - closed cup

Ponto de fulgor (°C)

227 °C - closed cup

Equipamento de proteção individual

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Maternal bisphenol-A levels at delivery: a looming problem?
Padmanabhan V, et al.
Journal of Perinatology : Official Journal of the California Perinatal Association, 28, 258-258 (2008)
Sanjay Basak et al.
Reproductive toxicology (Elmsford, N.Y.), 82, 72-79 (2018-10-24)
Humans are exposed to Bisphenol A (BPA) from the consumer products and plastic substances. However, impacts of low levels of BPA exposure on placental developmental processes such as first trimester trophoblast cell growth, angiogenesis and epigenetic modifications are not well
Germaine M Buck Louis et al.
Fertility and sterility, 100(1), 162-169 (2013-04-13)
To explore the relation between bisphenol A and 14 phthalate metabolites and endometriosis. Matched cohort design. Fourteen clinical centers. The operative cohort comprised 495 women undergoing laparoscopy/laparotomy, whereas the population cohort comprised 131 women matched on age and residence. None.
Maribel Casas et al.
Environment international, 56, 10-18 (2013-04-02)
Bisphenol A (BPA) exposure during early life may have endocrine-disrupting effects, but the dietary and sociodemographic predictors of BPA exposure during pregnancy and childhood remain unclear. Our aim was to evaluate the correlations between, and sociodemographic and dietary predictors of
Damaskini Valvi et al.
Epidemiology (Cambridge, Mass.), 24(6), 791-799 (2013-09-17)
Increasing experimental evidence suggests that prenatal bisphenol A (BPA) exposure induces offspring weight gain, but these effects remain largely unexplored in humans. We examined the effects of prenatal BPA exposure on postnatal growth and obesity. BPA concentrations were measured in

Protocolos

A comprehensive sample preparation and analytical procedure was developed by Supelco for determining BPA in drinking water.

HPLC Analysis of Bisphenol A, Dimethylbisphenol A and Nonylphenol on Ascentis® Express RP-Amide (UV Detection)

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