80198

Methoxatin disodium salt

≥97.0% (HPLC)

• Sinônimo(s): PQQ, Pyrrolo-quinoline-quinone disodium salt
• Fórmula empírica (Notação de Hill): C₁₄H₄N₂Na₂O₈
• Número CAS: 122628-50-6
• Peso molecular: 374.17
• Número MDL: MFCD00151711
• Código UNSPSC: 12352005
• ID de substância PubChem: 329768729
• NACRES: NA.79

Propriedades

• fonte biológica: fermentation/recombinant
• Nível de qualidade: 100
• Ensaio: ≥97.0% (HPLC)
• Formulário: powder
• cor: red-brown to deep orange; red-brown to deep red-brown
• temperatura de armazenamento: 2-8°C
• cadeia de caracteres SMILES: OC(=O)c1cc(nc2C(=O)C(=O)c3cc([nH]c3-c12)C(=O)O[Na])C(=O)O[Na]
• InChI: 1S/C14H6N2O8.2Na/c17-10-4-2-6(14(23)24)15-8(4)7-3(12(19)20)1-5(13(21)22)16-9(7)11(10)18;;/h1-2,15H,(H,19,20)(H,21,22)(H,23,24);;/q;2*+1/p-2
• chave InChI: UFVBOGYDCJNLPM-UHFFFAOYSA-L

Descrição

Descrição geral

Methoxatin/pyrroloquinoline quinone (PQQ) is mostly seen in plants, few bacteria and single cell eukaryotes, like yeast. It is mainly obtained from methylotrophic bacteria. PQQ may also present in the tissues of mammals.

Aplicação

• Safety assessment of a novel, dietary pyrroloquinoline quinone disodium salt (mnemoPQQ): This study investigates the safety profile of Methoxatin disodium salt, which has implications for its application in assay development for clinical and diagnostic purposes. Specifically, it addresses the compound′s use in dietary supplements and potential crossover into clinical assays where safety and toxicity are paramount (Shiojima et al., 2022).

Ações bioquímicas/fisiológicas

In bacteria, pyrroloquinoline quinone (PQQ) is used as a redox cycling cofactor. It acts as a cofactor (prosthetic group) for enzyme-catalyzed redox reactions of glucose and methanol dehydrogenase(s). PQQ is used in liposomes to establish a simple homogeneous assay for the detection of membrane permeabilization by antimicrobial peptides and synthetic copolymers. In bovine plasma amine oxidase, methoxatin may acts as the cofactor.

Informações de segurança

• Código de classe de armazenamento: 11 - Combustible Solids
• Classe de risco de água (WGK): WGK 3
• Ponto de fulgor (°F): Not applicable
• Ponto de fulgor (°C): Not applicable
• Equipamento de proteção individual: Eyeshields, Gloves, type N95 (US)