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74667

Sigma-Aldrich

Nourseothricin sulfate

≥85% (HPLC)

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About This Item

Número CAS:
Número MDL:
Código UNSPSC:
51102829
NACRES:
NA.85

fonte biológica

Streptomyces noursei

Nível de qualidade

Ensaio

≥85% (HPLC)

Formulário

solid

cor

white to light brown

solubilidade

H2O: soluble 200 mg/mL

adequação

suitable for (selection agent for molecular genetic research work)

espectro de atividade do antibiótico

Gram-negative bacteria
Gram-positive bacteria
fungi
mycobacteria
mycoplasma
parasites
viruses
yeast

Modo de ação

protein synthesis | interferes

temperatura de armazenamento

2-8°C

Descrição geral

Chemical structure: peptidyl nucleoside

Aplicação

Noursethricin is used as a dominant selection antibiotic for genetically modified bacteria, yeasts, fungi, protozoa and plants.

Ações bioquímicas/fisiológicas

Nourseothricin inhibits biosynthesis and induces miscoding. Resistance to nourseothricin is mediated by the sat1 encoded N-acetyltransferase. Nourseothricin is inactivated by acetylation of the β-amino group of the β-lysin.
Antifungal effective against Candida albicans. Candida species transformed with the gene encoding nourseothricin acetyltransferase (CaNAT1) were resistant to nourseothricin.

Embalagem

10mg, 100mg

Outras notas

Keep container tightly closed in a dry and well-ventilated place. Store under inert gas.

Pictogramas

Exclamation mark

Palavra indicadora

Warning

Frases de perigo

Declarações de precaução

Classificações de perigo

Acute Tox. 4 Oral

Código de classe de armazenamento

13 - Non Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves


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