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Key Documents

62962

Sigma-Aldrich

L-α-Lysophosphatidylcholine

egg yolk, ≥99.0% (TLC)

Sinônimo(s):

3-sn-Lysophosphatidylcholine, L-α-Lysolecithin

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About This Item

Número MDL:
MFCD00131444
Código UNSPSC:
51321705
NACRES:
NA.25

fonte biológica

egg yolk

descrição

zwitterionic

Ensaio

≥99.0% (TLC)

forma

powder or solid

composição

16:0, ~69% (fatty acid)
18:0, ~27% (fatty acid)
18:1, ~3% (fatty acid)

solubilidade

chloroform/methanol: 50 mg/mL, clear, colorless to very faintly yellow

grupo funcional

phospholipid

tipo de lipídio

phosphoglycerides

Condições de expedição

wet ice

temperatura de armazenamento

−20°C

Aplicação


  • The activation mode of the mechanosensitive ion channel, MscL, by lysophosphatidylcholine differs from tension-induced gating: L-α-LPC is explored for its unique interaction with ion channels, suggesting its potential as a tool for studying channel mechanics and developing new therapeutic strategies for diseases linked to cellular mechanics (Mukherjee et al., 2014).

  • Aerosol delivery of an enhanced helper-dependent adenovirus formulation to rabbit lung using an intratracheal catheter: The use of L-α-LPC in enhancing the delivery of gene therapy vectors via aerosol demonstrates its utility in improving the efficiency of gene therapies, particularly for respiratory diseases (Koehler et al., 2005).

Ações bioquímicas/fisiológicas

3-sn-Lysophosphatidylcholine, besides contributing to the positive curvature of membranes , inhibits SNARE complex disassembly in vitro and in rat nerve terminals and exocrine pancrease .

Outras notas

Preparation of demembranated frog sperm chromatin

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

Certificados de análise (COA)

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Trypanosomatid parasites are causative agents of neglected human diseases. Their lineage diverged early from the common eukaryotic ancestor, and they evolved singular mechanisms of gene expression that are crucial for their survival. Studies on unusual and essential molecular pathways lead
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