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Documentos Principais

52471

Sigma-Aldrich

Isotiocianato de fluoresceína–dextrana

average mol wt 2,000,000

Sinônimo(s):

FITC–Dextrana

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About This Item

Número CAS:
60842-46-8
Número MDL:
MFCD00131092
Código UNSPSC:
12352201
NACRES:
NA.32

fonte biológica

synthetic

Nível de qualidade

100

conjugado

FITC conjugate

Formulário

powder or crystals

peso molecular

average mol wt 2,000,000

Extensão da rotulagem

0.001-0.020 mol FITC per mol glucose (substitution)

fluorescência

λex 493 nm; λem 520 nm in 0.1 M Tris pH 8.0

aplicação(ões)

cell analysis

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Categorias relacionadas

Aplicação

Dextrana marcada com isotiocianato de fluoresceína para possível uso em estudos de perfusão em animais.
Fluorescein isothiocyanate–dextran (FITC–Dextran 2000) is use as a fluorescent probe to study the permeability of structures such as intercellular junctions involved in processes such as hearing and vascular permeability and the integrity of the blood brain barrier (BBB).

Pictogramas

Exclamation mark
GHS07

Palavra indicadora

Warning

Frases de perigo

H315,H319,H335

Classificações de perigo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Escolha uma das versões mais recentes:

Certificados de análise (COA)

Lot/Batch Number
BCCG5113
BCCD8600
BCCC2553
BCBZ3594
BCBW0983

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Visite a Biblioteca de Documentos

Elodie Debefve et al.
Lasers in surgery and medicine, 43(7), 696-704 (2011-11-08)
Photodynamic therapy (PDT) affects vascular barrier function and thus increases vessel permeability. This phenomenon may be exploited to facilitate targeted drug delivery and may lead to a new clinical application of photodynamic therapy. Here, we investigate the role of leukocyte
Albert Y Jin et al.
BMC neuroscience, 11, 12-12 (2010-02-04)
The link between early blood- brain barrier (BBB) breakdown and endothelial cell activation in acute stroke remain poorly defined. We hypothesized that P-selectin, a mediator of the early phase of leukocyte recruitment in acute ischemia is also a major contributor
Mercy Afadzi et al.
IEEE transactions on ultrasonics, ferroelectrics, and frequency control, 60(1), 21-33 (2013-01-05)
The mechanism involved in the ultrasoundenhanced intracellular delivery of fluorescein-isothiocyanate (FITC)-dextran (molecular weight 4 to 2000 kDa) and liposomes containing doxorubicin (Dox) was studied using HeLa cells and an ultrasound transducer at 300 kHz, varying the acoustic power. The cellular
Guiliang Zheng et al.
BMC neuroscience, 13, 71-71 (2012-06-21)
Exposure to intense noise causes the excessive movement of the organ of Corti, stretching the organ and compromising sensory cell functions. We recently revealed changes in the transcriptional expression of multiple adhesion-related genes during the acute phases of cochlear damage
Sangmi Ock et al.
Biochemical and biophysical research communications, 516(2), 350-356 (2019-06-19)
Receptor activator of NF-κB ligand (RANKL) is a member of the TNF superfamily. RANKL increases endothelial permeability and induces angiogenesis, suggesting its critical roles in the vasculature. Despite the evidence implicating RANKL in vascular pathology, its role in ischemic retinopathy
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Artigos

FITC-labelled polysaccharides

Additional information about FITC-labelled polysaccarides including FITC-Dextran, FITC-DEAE-dextran (FDD), FITC-carboxymethyl-dextran (FCM-Dextran). This page discusses the impact of weight-average molecular weight on the respective molecule dimensions and other physical properties

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