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21932

Sigma-Aldrich

5(6)-Carboxynaphthofluorescein

BioReagent, suitable for fluorescence, ≥90% (HPLC)

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About This Item

Fórmula empírica (Notação de Hill):
C29H16O7
Número CAS:
128724-35-6
Peso molecular:
476.43
Número MDL:
MFCD01862976
Código UNSPSC:
12352108
ID de substância PubChem:
329752223
NACRES:
NA.32

linha de produto

BioReagent

Ensaio

≥90% (HPLC)

Formulário

solid

pKa 

7.6

fluorescência

λex 512 nm; λem 567 nm (acid/neutral)
λex 598 nm; λem 668 nm (basic)

adequação

suitable for fluorescence

cadeia de caracteres SMILES

OC(=O)c1ccc2c(c1)C(=O)OC23c4ccc5cc(O)ccc5c4Oc6c3ccc7cc(O)ccc67.OC(=O)c8ccc9C(=O)OC%10(c%11ccc%12cc(O)ccc%12c%11Oc%13c%10ccc%14cc(O)ccc%13%14)c9c8

InChI

1S/2C29H16O7/c30-17-4-6-19-14(11-17)1-9-23-25(19)35-26-20-7-5-18(31)12-15(20)2-10-24(26)29(23)22-8-3-16(27(32)33)13-21(22)28(34)36-29;30-17-4-7-19-14(11-17)2-9-22-25(19)35-26-20-8-5-18(31)12-15(20)3-10-23(26)29(22)24-13-16(27(32)33)1-6-21(24)28(34)36-29/h2*1-13,30-31H,(H,32,33)

chave InChI

ANUHNEJUELPITC-UHFFFAOYSA-N

Aplicação

5(6)-Carboxynaphthofluorescein (CNF) may be used as an intravesicular pH-sensitive probe for the detection of activity, selectivity and cooperativity of ion channels such as gramicidin A.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

Eyeshields, Gloves, type N95 (US)

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Certificados de análise (COA)

Lot/Batch Number
BCCD2352
BCBW8708
BCBW3158
BCBT9341
BCBP0431V

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M Ramanathan et al.
Biosensors & bioelectronics, 22(12), 3001-3007 (2007-02-03)
The aim of the present work is to develop an evanescence wave array biosensor exploiting the "kinetic" approach of enzymatic reaction and further detection of the reaction products via pH sensitive fluorophore reporter. To demonstrate the feasibility of this approach
Shannon G Klein et al.
Global change biology, 23(9), 3690-3703 (2017-04-09)
Anthropogenic nutrient inputs enhance microbial respiration within many coastal ecosystems, driving concurrent hypoxia and acidification. During photosynthesis, Symbiodinium spp., the microalgal endosymbionts of cnidarians and other marine phyla, produce O
D A Jankowska et al.
Biosensors & bioelectronics, 87, 312-319 (2016-08-31)
Aging population and longer life expectancy are the main reasons for an increasing number of patients with wound problems. Although the interest in wound care increases continuously, wound management still remains a challenge mainly due to the higher occurrence of
Sara M Butterfield et al.
Organic & biomolecular chemistry, 7(9), 1784-1792 (2009-07-11)
The activity of synthetic pores, ion channels, transporters and carriers is usually determined with fluorescent probes in vesicles or by conductance measurements in planar lipid bilayers. Elaborating on more colorful alternatives, we here introduce 5(6)-carboxynaphthofluorescein (CNF) as an intravesicular pH
A Song et al.
Analytical chemistry, 69(5), 863-867 (1997-03-01)
A fast and durable ratiometric pH microoptode that is highly accurate, precise, sensitive, reversible, and reproducible over the physiological ranges of pH, ionic strength, and temperature has been developed. The sensing site consists of 5 (and 6)-carboxynaphthofluorescein (CNF) entrapped in

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