Pular para o conteúdo
Merck
Todas as fotos(1)

Documentos

17928

Sigma-Aldrich

O-Methyl-O′-succinylpolyethylene glycol 2′000

Sinônimo(s):

Polyethylene glycol, O-(Succinyl)-O′-methylpolyethylene glycol 2′000, Polyethylene glycol 2′000 monomethyl ether succinate

Faça loginpara ver os preços organizacionais e de contrato
Todas as fotos(1)

About This Item

Fórmula linear:
CH3O(CH2CH2O)nCOCH2CH2COOH
Número CAS:
31961-02-1
Número MDL:
MFCD00284260
Código UNSPSC:
51171641
NACRES:
NA.26

forma

powder

peso molecular

Mr ~2100

pf

50-53 °C

Ω-final

carboxylic acid

α-final

methoxy

temperatura de armazenamento

−20°C

Aplicação

Polyethylene glycol 2000 is used in the construction of biomaterials such as biopolymers, micelles and nanostructures.

Ações bioquímicas/fisiológicas

O-Methyl-O′-succinylpolyethylene glycol 2′000 is a modified monomethoxypolyethylene glycol (mPEG) wherein the hydroxyl groups are succinylated by succinic anhydride. This succinylated mPEG can then be used to synthesize tolerogenic mPEG conjugates of peptides. Tolerogenic peptide conjugates are very effective reagents for obtaining epitope-specific immunosuppression of antibody responses to immunopathogenic sites on multideterminant complex protein antigens.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves

Certificados de análise (COA)

Busque Certificados de análise (COA) digitando o Número do Lote do produto. Os números de lote e remessa podem ser encontrados no rótulo de um produto após a palavra “Lot” ou “Batch”.

Já possui este produto?

Encontre a documentação dos produtos que você adquiriu recentemente na biblioteca de documentos.

Visite a Biblioteca de Documentos

Os clientes também visualizaram

Slide 1 of 5

1 of 5

mPEG10K-Succinimidyl Carboxymethyl Ester average Mn 10,000

Sigma-Aldrich

JKA3016

mPEG10K-Succinimidyl Carboxymethyl Ester

4-Azidobenzoic acid solution ~0.2 M in tert-butyl methyl ether, ≥95.0% (HPLC)

Sigma-Aldrich

778877

4-Azidobenzoic acid solution

Poly(ethylene glycol) methyl ether average Mn ~2,000

Sigma-Aldrich

202509

Poly(ethylene glycol) methyl ether

Poli(etilenoglicol) 2000, for synthesis

Sigma-Aldrich

8.21037

Poli(etilenoglicol)

DCC 99%

Sigma-Aldrich

D80002

DCC

Antitumor effect of liposomal histone deacetylase inhibitor-lipid conjugates in vitro.
Hattori Y, Nagaoka Y, Kubo M, et al.
Chemical & Pharmaceutical Bulletin, 59, 1389-1392 (2011)
Gulam Mustafa Hasan et al.
Journal of parasitology research, 2011, 120462-120462 (2011-07-21)
We have examined the effect of stearylamine (SA) in liposomes on the viability of Plasmodium falciparum in culture by studying the inhibition of incorporation of [(3)H]-hypoxanthine in the nucleic acid of parasites. Stearylamine in liposomes significantly inhibits the growth of
Ayman El-Sayed et al.
Journal of pharmaceutical sciences, 101(2), 879-882 (2011-11-17)
We previously reported on a stearylated INF7 peptide (str-INF7), which enhances the endosomal escape of an octaarginine (R8)-modified liposomal particle encapsulating plasmid DNA (pDNA) in a fusion-independent manner. This study examined whether this peptide derivative enhanced the endosomal escape and
Peptide/protein-polymer conjugates: synthetic strategies and design concepts.
Gauthier MA, Klok HA.
Chemical Communications (Cambridge, England), 21, 2591-2611 (2008)
Sabrina Hoffmann et al.
Immunology letters, 136(1), 13-20 (2010-11-30)
T-cell recognition of peptide-MHC complexes on APCs requires cell-cell interactions. The molecular events leading to T-cell activation have been extensively investigated, but the underlying physical binding forces between T-cells and APCs are largely unknown. We used single cell force spectroscopy
Exibir todos os documentos relacionados

Artigos

Synthesis of Magnetic Nanoparticles for Biosensing

Professor Randal Lee (University of Houston, USA) discusses design considerations for iron oxide magnetic nanospheres and nanocubes used for biosensing, including synthetic procedures, size, and shape. The effects of these variables are discussed for various volumetric-based and surface-based detection schemes.

Nossa equipe de cientistas tem experiência em todas as áreas de pesquisa, incluindo Life Sciences, ciência de materiais, síntese química, cromatografia, química analítica e muitas outras.

Entre em contato com a assistência técnica