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Documentos Principais

00017

Sigma-Aldrich

Acacetin

≥97.0% (HPLC)

Sinônimo(s):

4′-Methylapigenin, 5,7-Dihydroxy-4′-methoxyflavone, Apigenin 4′-methyl ether, Buddleoflavonol, Linarigenin

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About This Item

Fórmula empírica (Notação de Hill):
C16H12O5
Número CAS:
Peso molecular:
284.26
Beilstein:
277879
Número CE:
Número MDL:
Código UNSPSC:
12352200
eCl@ss:
32150233
ID de substância PubChem:
NACRES:
NA.47

Nível de qualidade

Ensaio

≥97.0% (HPLC)

Formulário

powder or crystals

pf

260-265 °C (lit.)

aplicação(ões)

metabolomics
vitamins, nutraceuticals, and natural products

temperatura de armazenamento

2-8°C

cadeia de caracteres SMILES

COc1ccc(cc1)C2=CC(=O)c3c(O)cc(O)cc3O2
COc1ccc(cc1)C2=CC(=O)c3c(O)cc(O)cc3O2

InChI

1S/C16H12O5/c1-20-11-4-2-9(3-5-11)14-8-13(19)16-12(18)6-10(17)7-15(16)21-14/h2-8,17-18H,1H3

chave InChI

DANYIYRPLHHOCZ-UHFFFAOYSA-N

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Descrição geral

Acacetin belongs to the category of naturally occurring plant pigments called flavonoids found in vascular plants. It was first reported to be extracted from the leaves of Robinia pseuducacia. It has been used as an active component of traditional Chinese medicine Xuelianhua.

Ações bioquímicas/fisiológicas

Acacetin has been noted to exhibit anti-peroxidative, anti-inflammatory, and anti-plasmodial properties. It has been posited to prevent the proliferation of Hep G2 cells, thereby causing cell apoptosis and subsequent anti-cancer action. It has antiarrhythmic properties and can be used in the treatment of Atrial fibrillation.
Flavonoid with anti-peroxidative and anti-inflammatory properties. Used in traditional Chinese medicine.
Flavonoid with anti-peroxidative and anti-inflammatory properties. Used in traditional Chinese medicine. It has been recognized as an antiproliferative agent on cancer cell lines by inducing apoptosis and blocking cell cycle progression in the G1 phase.

Embalagem

Bottomless glass bottle. Contents are inside inserted fused cone.

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

Equipamento de proteção individual

dust mask type N95 (US), Eyeshields, Gloves


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Pinobanksin ≥95% (HPLC)

Sigma-Aldrich

68530

Pinobanksin

Acacetin, a natural flavone, selectively inhibits human atrial repolarization potassium currents and prevents atrial fibrillation in dogs
Li GR, et al.,
Circulation, 117(19), 2449-2457 (2008)
Acacetin inhibits the proliferation of Hep G2 by blocking cell cycle progression and inducing apoptosis
Hsu YL, et al.,
Biochemical Pharmacology, 67(5), 823-829 (2004)
V Zimkhitha Sotenjwa et al.
Fitoterapia, 147, 104740-104740 (2020-10-12)
Artemisia afra (African wormwood) is a popular medicinal plant of southern Africa and is an excellent candidate for commercialisation. This current study was aimed at exploring the phytochemistry and chemical variation of non-volatile compounds within wild populations of A. afra
Antifungal and antioxidant activities of heartwood, bark, and leaf extracts of Robinia pseudoacacia
Hosseinihashemi SK, et al.
BioResources, 11(1), 1634-1646 (2016)
Jidan Liu et al.
Carbohydrate research, 357, 41-46 (2012-06-27)
Apigenin-7-O-β-D-glycosides 1-8 and acacetin-7-O-β-D-glycosides 9-16 were semisynthesized from 4'-O-benzyl apigenin 17 and acacetin 18 by glycosidation and deprotection with the corresponding α-acetylglycosyl bromide, respectively. Compounds 17 and 18 were prepared by iodination followed by base-induced elimination, 4'-O-benzylation, or 4'-O-methylation and

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