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S0882

Sigma-Aldrich

Sodium selenate

≥95% (elemental analysis)

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About This Item

Fórmula linear:
Na2SeO4
Número CAS:
Peso molecular:
188.94
Número CE:
Número MDL:
Código UNSPSC:
12352302
ID de substância PubChem:
NACRES:
NA.55
Ensaio:
≥95% (elemental analysis)
Formulário:
powder or crystals

Nível de qualidade

Ensaio

≥95% (elemental analysis)

Formulário

powder or crystals

pH

5.5-7.5 (25 °C, 18.9 g/L)

cadeia de caracteres SMILES

[Na+].[Na+].[O-][Se]([O-])(=O)=O

InChI

1S/2Na.H2O4Se/c;;1-5(2,3)4/h;;(H2,1,2,3,4)/q2*+1;/p-2

chave InChI

MHQOTKLEMKRJIR-UHFFFAOYSA-L

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Aplicação


  • Selenium nanoparticles alleviate ischemia reperfusion injury-induced acute kidney injury by modulating GPx-1/NLRP3/Caspase-1 pathway.: This study demonstrates that selenium nanoparticles, including sodium selenate, mitigate acute kidney injury caused by ischemia reperfusion. The nanoparticles modulate key pathways, offering potential therapeutic applications in renal injury treatment (Wang et al., 2022).

  • Phosphoproteomic profiling of selenate-treated Alzheimer′s disease model cells.: This research provides a detailed phosphoproteomic profile of Alzheimer′s disease model cells treated with sodium selenate, uncovering its effects on protein phosphorylation and implications for neuroprotection (Chen et al., 2014).

Palavra indicadora

Danger

Classificações de perigo

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Irrit. 2 - STOT RE 2

Código de classe de armazenamento

6.1B - Non-combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de risco de água (WGK)

WGK 2

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable


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Maria Łabanowska et al.
Journal of plant physiology, 169(3), 275-284 (2011-12-14)
Biochemical analyses of antioxidant content were compared with measurements of fluorescence and electron paramagnetic resonance (EPR) to examine the alteration of radicals in wheat seedlings exposed to 2 days of selenium stress. Two genotypes of Polish and one of Finnish
Adam J Matich et al.
Phytochemistry, 75, 140-152 (2011-12-27)
Glucosinolates are sulphur-containing glycosides found in many Brassica spp. that are important because their aglycone hydrolysis products protect the plant from herbivores and exhibit anti-cancer properties in humans. Recently, synthetically produced selenium analogues have been shown to be more effective
M Djanaguiraman et al.
Plant physiology and biochemistry : PPB, 48(12), 999-1007 (2010-10-19)
Oxidative stress is commonly induced when plants are grown under high temperature (HT) stress conditions. Selenium often acts as an antioxidant in plants; however, its role under HT-induced oxidative stress is not definite. We hypothesize that selenium application can partly
Nigel C Jones et al.
Neurobiology of disease, 45(3), 897-901 (2011-12-21)
Tau hyperphosphorylation has been implicated in the pathogenesis of a variety of forms of human epilepsy. Here we investigated whether treatment with sodium selenate, a drug which reduces pathological hyperphosphorylated tau by enhancement of PP2A activity, would inhibit seizures in
N M Corcoran et al.
British journal of cancer, 103(4), 462-468 (2010-07-22)
Angiogenesis is fundamental to the progression of many solid tumours including prostate cancer. Sodium selenate is a small, water-soluble, orally bioavailable activator of PP2A phosphatase with anti-angiogenic properties. This was a dose-escalation phase I study in men with asymptomatic, chemotherapy-naïve

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