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Y0001289

Magnolol

European Pharmacopoeia (EP) Reference Standard

Sinônimo(s):

2,2′-Bichavicol, 5,5′-Diallyl-2,2′-biphenyldiol

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About This Item

Fórmula empírica (Notação de Hill):
C18H18O2
Número CAS:
528-43-8
Peso molecular:
266.33
Número MDL:
MFCD00016658
Código UNSPSC:
41116107
ID de substância PubChem:
329831345
NACRES:
NA.24

grau

pharmaceutical primary standard

família API

magnolol, magnolia officialis

fabricante/nome comercial

EDQM

aplicação(ões)

pharmaceutical (small molecule)

formato

neat

temperatura de armazenamento

−20°C

cadeia de caracteres SMILES

Oc1ccc(CC=C)cc1-c2cc(CC=C)ccc2O

InChI

1S/C18H18O2/c1-3-5-13-7-9-17(19)15(11-13)16-12-14(6-4-2)8-10-18(16)20/h3-4,7-12,19-20H,1-2,5-6H2

chave InChI

VVOAZFWZEDHOOU-UHFFFAOYSA-N

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Descrição geral

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Aplicação

Magnolol EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Ações bioquímicas/fisiológicas

Magnolol is a bioactive plant component isolated from the root and stem bark of Magnolia officinalis with antifungal, antibacterial and antioxidant effects. Magnolol also demonstrates anti-inflammatory activity by interferring with NF-κB signaling. It also appears to have anti-inflammatory properties related to vascular disorders such as atherosclerosis due to its ability to inhibit IL-6-induced STAT3 activation.

Embalagem

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Outras notas

Sales restrictions may apply.

Palavra indicadora

Danger

Frases de perigo

H315,H318,H335,H411

Classificações de perigo

Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

Órgãos-alvo

Respiratory system

Código de classe de armazenamento

11 - Combustible Solids

Classe de risco de água (WGK)

WGK 3

Ponto de fulgor (°F)

Not applicable

Ponto de fulgor (°C)

Not applicable

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Certificados de análise (COA)

Lot/Batch Number

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Yong Zhang et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(23), 3526-3530 (2013-03-13)
Magnolol is one of main active constituents from Magnolia officinalis, a widely used traditional Chinese medicine. Previous studies have proved its multiple pharmacological effects, such as anti-oxidation, anti-microbial and anti-tumor. In recent years, more and more studies have focused on
A-Rang Im et al.
Environmental toxicology and pharmacology, 39(1), 417-423 (2015-01-07)
In this study, we evaluated the anti-photoaging activity of magnolol in UV-irradiated hairless mice, and hypothesized that magnolol would prevent photoaging in these animals. The inhibitory effect of magnolol on wrinkle formation was determined by analyzing the skin replica, histologically
Jui-Lung Shen et al.
Molecules (Basel, Switzerland), 15(9), 6452-6465 (2010-09-30)
Chinese herbs have been and still are widely used as important remedies in Oriental medicine. Over the recent years, a variety of biologically active constituents have been isolated from these sources and confirmed to have multifunctional activity in experimental studies.

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